Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.54 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.54 |
| ▸ | HMGCR | P04035 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10795660 | 1.00 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1HMGCRCYP3A4TSHR | |
| SCHEMBL10795247 | 0.82 | CYSLTR2 (0.65) | CYSLTR2CYSLTR1HMGCRCYP3A4TSHR | |
| SCHEMBL10797605 | 0.82 | CYSLTR2 (0.65) | CYSLTR2CYSLTR1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL10794942 | 0.82 | CYSLTR2 (0.65) | CYSLTR2CYSLTR1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL10794950 | 0.82 | CYSLTR2 (0.65) | CYSLTR2CYSLTR1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL4947296 | 0.82 | CYP3A4 (0.54) | CYSLTR2CYSLTR1HMGCRCYP3A4TSHR | |
| SCHEMBL29941829 | 0.82 | CYP3A4 (0.54) | CYSLTR2CYSLTR1HMGCRCYP3A4TSHR | |
| SCHEMBL4947304 | 0.82 | CYP3A4 (0.54) | CYSLTR2CYSLTR1HMGCRCYP3A4TSHR | |
| SCHEMBL10980153 | 0.82 | CYP3A4 (0.54) | CYSLTR2CYSLTR1HMGCRCYP3A4TSHR | |
| SCHEMBL10978168 | 0.82 | CYP3A4 (0.54) | CYSLTR2CYSLTR1HMGCRCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207599-A1 | Arachidonic acid analogues | BEECHAM GROUP PLC (GB) | 1987-01-07 | — | — | EP | claimed |
| EP-0207599-A1 | Arachidonic acid analogues | BEECHAM GROUP PLC (GB) | 1987-01-07 | — | — | EP | disclosed |