Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941829 | 1.00 | CYP3A4 (0.54) | CYP3A4TSHRKDM4EMAPTHSD17B10 | |
| SCHEMBL4947304 | 1.00 | CYP3A4 (0.54) | CYP3A4TSHRKDM4EMAPTHSD17B10 | |
| SCHEMBL10978168 | 1.00 | CYP3A4 (0.54) | CYP3A4TSHRKDM4EMAPTHSD17B10 | |
| SCHEMBL10980153 | 1.00 | CYP3A4 (0.54) | CYP3A4TSHRKDM4EMAPTHSD17B10 | |
| SCHEMBL14299984 | 0.88 | CYP3A4 (0.52) | CYP3A4TSHRKDM4EMAPTHSD17B10 | |
| SCHEMBL10739385 | 0.86 | CYP3A4 (0.51) | CYP3A4TSHRKDM4EMAPTHSD17B10 | |
| SCHEMBL10739390 | 0.86 | CYP3A4 (0.51) | CYP3A4TSHRKDM4EMAPTHSD17B10 | |
| SCHEMBL10666959 | 0.83 | FFAR1 (0.40) | CYP3A4TSHRKDM4EMAPTHSD17B10 | |
| SCHEMBL10666954 | 0.83 | FFAR1 (0.40) | CYP3A4TSHRKDM4EMAPTHSD17B10 | |
| SCHEMBL8698375 | 0.82 | CA1 (0.47) | CYP3A4KDM4EMAPTALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1666883-A1 | Diagnostic and monitoring methods for bone loss | F. Hoffmann-La Roche AG (CH) | 2006-06-07 | — | — | EP | claimed |
| EP-1634618-B1 | Method for identifying compounds that increase bone mineral density | HOFFMANN LA ROCHE (CH) | 2008-02-13 | — | — | EP | disclosed |
| EP-1666883-A1 | Diagnostic and monitoring methods for bone loss | F. Hoffmann-La Roche AG (CH) | 2006-06-07 | — | — | EP | disclosed |
| US-20060079488-A1 | Methods of treating and preventing bone loss | ALLARD JOHN D | 2006-04-13 | — | — | US | disclosed |
| EP-1634618-A1 | Method for identifying compounds that increase bone mineral density | F. Hoffmann-La Roche AG (CH) | 2006-03-15 | — | — | EP | disclosed |
| US-20030175680-A1 | Methods of treating and preventing bone loss | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079488-A1 | Methods of treating and preventing bone loss | ALOX5, SOST, ALOX15B | CYP3A4 4217/4885TSHR 3339/4885KDM4E 1432/4885 |
| US-20030175680-A1 | Methods of treating and preventing bone loss | ALOX5, SOST, ALOX15B | CYP3A4 4217/4885TSHR 3339/4885KDM4E 1432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.