Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | CASP7 | P55210 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10790823 | 0.85 | ALDH1A1 (0.68) | KDM4EKMT2AALDH1A1CA12CA9 | |
| SCHEMBL31623112 | 0.85 | ALDH1A1 (0.68) | KDM4EKMT2AALDH1A1CA12CA9 | |
| SCHEMBL5341818 | 0.81 | KDM4E (0.72) | PIM1KDM4EKMT2AALDH1A1ESR2 | |
| SCHEMBL29096988 | 0.78 | PRKDC (0.51) | PIM1KDM4EALDH1A1CA12CA9 | |
| SCHEMBL10792023 | 0.78 | KDM4E (0.53) | PIM1KDM4EKMT2AALDH1A1ESR2 | |
| SCHEMBL128001 | 0.78 | KDM4E (0.74) | KDM4EKMT2AALDH1A1ESR2ESR1 | |
| SCHEMBL10793717 | 0.78 | KDM4E (0.53) | PIM1KDM4EKMT2AALDH1A1ESR2 | |
| SCHEMBL31506370 | 0.78 | ALDH1A1 (0.51) | PIM1KDM4EKMT2AALDH1A1HPGD | |
| SCHEMBL8704287 | 0.77 | HSD17B3 (0.55) | PIM1KDM4EKMT2AALDH1A1ESR2 | |
| SCHEMBL10792047 | 0.75 | HSD17B3 (0.76) | KDM4EKMT2AALDH1A1ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111746-B1 | SULFONIC-ACID ESTERS OF HYDROXYCOUMARINES, THEIR PREPARATION AND MEDICINES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1987-09-16 | — | — | EP | disclosed |
| US-4618622-A | ANTIDEPRESSANTS, ANTIALLERGENS | BASF AKTIENGESELLSCHAFT (DE) | 1986-10-21 | — | — | US | disclosed |
| EP-0111746-A2 | Sulfonic-acid esters of hydroxycoumarines, their preparation and medicines containing them | BASF Aktiengesellschaft (DE) | 1984-06-27 | — | — | EP | disclosed |