SCHEMBL5341818

SCHEMBL5341818

O=c1cc(O)c2cc(O)ccc2o1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.72
KMT2A Q03164 4/20 0.72
ALDH1A1 P00352 3/20 0.72
PIM1 P11309 1/20 0.68
CA12 O43570 5/20 0.63
CA9 Q16790 5/20 0.63
CA1 P00915 2/20 0.63
ESR2 Q92731 3/20 0.55
ESR1 P03372 2/20 0.55
MCL1 Q07820 3/20 0.53
HSD17B3 P37058 4/20 0.53
MAOA P21397 3/20 0.53
HPGD P15428 3/20 0.53
HSD17B10 Q99714 3/20 0.53
AKR1B1 P15121 3/20 0.53
LMNA P02545 2/20 0.53
GLA P06280 2/20 0.53
GAA P10253 2/20 0.53
CASP1 P29466 2/20 0.53
CASP7 P55210 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29419327 0.84 ALDH1A1 (1.00) KDM4EKMT2AALDH1A1CA12CA9
SCHEMBL958685 0.84 ALDH1A1 (1.00) KDM4EKMT2AALDH1A1CA12CA9
Water SCHEMBL11848480 0.82 ALDH1A1 (0.96) KDM4EKMT2AALDH1A1CA12CA9
SCHEMBL128001 0.81 KDM4E (0.74) KDM4EKMT2AALDH1A1CA12CA9
SCHEMBL2490464 0.81 PIM1 (0.64) KDM4EKMT2AALDH1A1PIM1CA12
SCHEMBL10793717 0.81 KDM4E (0.53) KDM4EKMT2AALDH1A1PIM1CA12
SCHEMBL2761544 0.81 PIM1 (1.00) KDM4EKMT2AALDH1A1PIM1CA12
SCHEMBL10792023 0.81 KDM4E (0.53) KDM4EKMT2AALDH1A1PIM1CA12
SCHEMBL10795669 0.81 PIM1 (0.54) KDM4EKMT2AALDH1A1PIM1CA12
SCHEMBL5336545 0.81 PIM1 (0.64) KDM4EKMT2AALDH1A1PIM1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117721161-A Biological-based multifunctional anti-aging auxiliary agent, and preparation method and application thereof 四川大学 2024-03-19 CN claimed
CN-108598533-B Coumarin-based photocyclization crosslinking sulfonated polyimide proton exchange membrane and preparation method thereof 同济大学 2020-11-03 CN claimed
CN-108598533-A Cyclization cross-linked polyimide proton exchange membrane based on cumarin and preparation method thereof 同济大学 2018-09-28 CN claimed
CN-118834490-A Photo-crosslinkable perfluorinated ion membrane and preparation method thereof 上海交通大学 2024-10-25 CN disclosed
CN-117721161-A Biological-based multifunctional anti-aging auxiliary agent, and preparation method and application thereof 四川大学 2024-03-19 CN disclosed
EP-4317284-A1 COMPOSITION FOR FLUORINE RUBBER CROSSLINKING AND MOLDED ARTICLE Daikin Industries, Ltd. (JP) 2024-02-07 EP disclosed
US-20240034856-A1 COMPOSITION FOR FLUORINE RUBBER CROSSLINKING AND MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2024-02-01 US disclosed
CN-117043260-A Composition for cross-linking fluororubber and molded article 大金工业株式会社 2023-11-10 CN disclosed
WO-2022210044-A1 COMPOSITION FOR FLUORINE RUBBER CROSSLINKING AND MOLDED ARTICLE ダイキン工業株式会社 2022-10-06 WO disclosed
US-11141402-B2 Compounds useful in inhibiting human trefoil factor 3 NATIONAL UNIVERSITY OF SINGAPORE (SG) 2021-10-12 US disclosed
EP-3848367-A1 TRICYCLIC COMPOUNDS ACTING ON CRBN PROTEINS Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) 2021-07-14 EP disclosed
CN-1254338-A Process for preparing photoactive coumarin derivatives HOECHST CELANESE CORP (CH) 2000-05-24 CN disclosed
EP-0977747-A1 PHOTOACTIVE COUMARIN DERIVATIVES CLARIANT INTERNATIONAL LTD. (CH) 2000-02-09 EP disclosed
EP-0968202-A1 PROCESS FOR PREPARING PHOTOACTIVE COUMARIN DERIVATIVES CLARIANT INTERNATIONAL LTD. (CH) 2000-01-05 EP disclosed
EP-0950655-A1 AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME CHEMIPRO KASEI KAISHA, LIMITED (JP) 1999-10-20 EP disclosed
WO-1998039317-A1 PROCESS FOR PREPARING PHOTOACTIVE COUMARIN DERIVATIVES CLARIANT INTERNATIONAL LTD. (CH) 1998-09-11 WO disclosed
WO-1998039319-A1 PHOTOACTIVE COUMARIN DERIVATIVES CLARIANT INTERNATIONAL LTD. (CH) 1998-09-11 WO disclosed
EP-0442655-B1 Benzisoxazole derivatives ZENECA LTD (GB) 1996-01-17 EP disclosed
US-5176737-A BENZISOXAZOLE COMPOUNDS USEFUL AS HERBICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-01-05 US disclosed
EP-0442655-A2 Benzisoxazole derivatives ZENECA LIMITED (GB) 1991-08-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11141402-B2 Compounds useful in inhibiting human trefoil factor 3 ETF1, F3, DNASE1L3 KDM4E 3966/4885KMT2A 4155/4885ALDH1A1 3051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.