SCHEMBL1079583

SCHEMBL1079583

COCC(N)C(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL750155 1.00
SCHEMBL1697378 1.00
Hydrochloric Acid SCHEMBL2715574 1.00
Hydrochloric Acid SCHEMBL2715572 1.00
Propionic Acid SCHEMBL28095701 0.89 FFAR3 (0.42)
Hydrochloric Acid SCHEMBL4900678 0.83 DDAH1 (0.41)
SCHEMBL127189 0.79
SCHEMBL12965970 0.79
Hydrochloric Acid SCHEMBL856592 0.79
SCHEMBL14870685 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103911404-B A kind of scheme for lacosamide chemical-enzymatic preparation method NANJING UNIVERSITY (CN) 2016-01-20 CN claimed
WO-2013072933-A2 PROCESS FOR PREPARATION OF 2-ACETAMIDO-N-BENZYL-3-METHOXYPROPIONAMIDE GLENMARK GENERICS LIMITED (IN) 2013-05-23 WO claimed
US-20180092915-A1 SODIUM CHANNEL BLOCKERS FOR SKIN DISORDERS PARION SCIENCES, INC. (US) 2018-04-05 US disclosed
US-9849129-B2 Sodium channel blockers for skin disorders PARION SCIENCES, INC. (US) 2017-12-26 US disclosed
WO-2016133967-A2 SODIUM CHANNEL BLOCKERS FOR SKIN DISORDERS PARION SCIENCES, INC. (US) 2016-08-25 WO disclosed
CN-103282352-B Benzamides and nicotinamide as SYK regulator 波托拉医药品公司 2016-08-10 CN disclosed
CN-103911404-B A kind of scheme for lacosamide chemical-enzymatic preparation method NANJING UNIVERSITY (CN) 2016-01-20 CN disclosed
CN-103911404-B A kind of scheme for lacosamide chemical-enzymatic preparation method NANJING UNIVERSITY (CN) 2016-01-20 CN disclosed
US-8933065-B2 N-benzylamide substituted derivatives of 2-(acylamido)acetic acid and 2-(acylamido)propionic acids: potent neurological agents THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2015-01-13 US disclosed
US-20140342989-A1 Novel N-Benzylamide Substituted Derivatives of 2-(Acylamido)acetic Acid and 2-(Acylamido)propionic Acids: Potent Neurological Agents NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2014-11-20 US disclosed
EP-2262764-B1 NOVEL N-BENZYLAMIDE SUBSTITUTED DERIVATIVES OF 2-(ACYLAMIDO)ACETIC ACID AND 2-(ACYLAMIDO)PROPIONIC ACIDS: POTENT NEUROLOGICAL AGENTS UNIV NORTH CAROLINA (US) 2014-11-12 EP disclosed
WO-2011037833-A2 NOVEL N-BENZYLAMIDE SUBSTITUTED DERIVATIVES OF 2-(ACYLAMIDO)ACETIC ACID AND 2-(ACYLAMIDO)PROPIONIC ACIDS: POTENT NEUROLOGICAL AGENTS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2011-03-31 WO disclosed
US-20110021482-A1 Novel N-Benzylamide Substituted Derivatives of 2-(Acylamido)acetic Acid and 2-(Acylamido)propionic Acids: Potent Neurological Agents UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE 2011-01-27 US disclosed
EP-2262764-A2 NOVEL N-BENZYLAMIDE SUBSTITUTED DERIVATIVES OF 2-(ACYLAMIDO)ACETIC ACID AND 2-(ACYLAMIDO)PROPIONIC ACIDS: POTENT NEUROLOGICAL AGENTS The University of North Carolina At Chapel Hill (US) 2010-12-22 EP disclosed
WO-2009145816-A2 NOVEL N-BENZYLAMIDE SUBSTITUTED DERIVATIVES OF 2-(ACYLAMIDO)ACETIC ACID AND 2-(ACYLAMIDO)PROPIONIC ACIDS: POTENT NEUROLOGICAL AGENTS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2009-12-03 WO disclosed
EP-1758606-A1 NOVEL USE OF PEPTIDE COMPOUNDS FOR TREATING ESSENTIAL TREMOR AND OTHER TREMOR SYNDROMES SCHWARZ PHARMA AG (DE) 2007-03-07 EP disclosed
WO-2006000397-A1 NOVEL USE OF PEPTIDE COMPOUNDS FOR TREATING ESSENTIAL TREMOR AND OTHER TREMOR SYNDROMES SCHWARZ PHARMA AG (DE) 2006-01-05 WO disclosed
EP-1284961-A1 GLYCINAMIDES MERCK PATENT GmbH (DE) 2003-02-26 EP disclosed
WO-2001092219-A1 GLYCINAMIDES MERCK PATENT GMBH (DE) 2001-12-06 WO disclosed
WO-2001007409-A1 CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS ASTRAZENECA UK LIMITED (GB) 2001-02-01 WO disclosed