⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1079583 | 1.00 | — | — | |
| SCHEMBL1697378 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL2715574 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL2715572 | 1.00 | — | — | |
| Propionic Acid SCHEMBL28095701 | 0.89 | FFAR3 (0.42) | — | |
| Hydrochloric Acid SCHEMBL4900678 | 0.83 | DDAH1 (0.41) | — | |
| SCHEMBL127189 | 0.79 | — | — | |
| SCHEMBL12965970 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL856592 | 0.79 | — | — | |
| SCHEMBL14870685 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103911404-B | A kind of scheme for lacosamide chemical-enzymatic preparation method | NANJING UNIVERSITY (CN) | 2016-01-20 | — | — | CN | claimed |
| CN-101563339-A | 2-benzimidazolyl-6-morpholino-4- (azetidine, pyrrolidine, piperidine or aza ) pyrimidine derivatives as P I3K and MtToR inhibitors for the treatment of proliferative diseases | ASTRAZENECA AB (SE) | 2009-10-21 | — | — | CN | claimed |
| CN-101535296-A | 2-benzimidazolyl-6-morpholino-4-phenylpyrimidine derivatives as pi3k and mtor inhibitors for the treatment of proliferative disorders | ASTRAZENECA AB (SE) | 2009-09-16 | — | — | CN | claimed |
| US-20230257410-A1 | PHENOTHIAZINE DERIVATIVES AND USES THEREOF | CAMP4 THERAPEUTICS CORPORATION | 2023-08-17 | — | — | US | disclosed |
| CN-103911404-B | A kind of scheme for lacosamide chemical-enzymatic preparation method | NANJING UNIVERSITY (CN) | 2016-01-20 | — | — | CN | disclosed |
| EP-1439174-B1 | 4-IMIDAZOLIN-2-ONE COMPOUNDS AS p38 MAP KINASE INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-7846933-B2 | such as 1-(4-Fluorophenyl)-5-(pyridin-4-yl)-4-imidazolin-2-one, having excellent p38 MAP kinase inhibitory action, useful for the treatment of osteoarthritis, arthritis, ulcerative colitis, Crohn's disease, psoriasis, dermatitis, asthma, bronchitis, pneumonia, rhinitis, conjunctivitis or keratitis | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-12-07 | — | — | US | disclosed |
| WO-2009139948-A1 | POLY AROMATIC SODIUM CHANNEL BLOCKERS | JOHNSON MICHAEL R (US) | 2009-11-19 | — | — | WO | disclosed |
| CN-101563339-A | 2-benzimidazolyl-6-morpholino-4- (azetidine, pyrrolidine, piperidine or aza ) pyrimidine derivatives as P I3K and MtToR inhibitors for the treatment of proliferative diseases | ASTRAZENECA AB (SE) | 2009-10-21 | — | — | CN | disclosed |
| CN-101535296-A | 2-benzimidazolyl-6-morpholino-4-phenylpyrimidine derivatives as pi3k and mtor inhibitors for the treatment of proliferative disorders | ASTRAZENECA AB (SE) | 2009-09-16 | — | — | CN | disclosed |
| US-20090088422-A1 | 4-IMIDAZOLIN-2-ONE COMPOUNDS | KUBO AKIRA | 2009-04-02 | — | — | US | disclosed |
| WO-2008124496-A1 | METHOD OF TREATING ACID-SENSING ION CHANNEL MEDIATED PAIN, COUGH, AND CENTRAL NERVOUS SYSTEM DISORDERS | PARION SCIENCES, INC. (US) | 2008-10-16 | — | — | WO | disclosed |
| CN-101014590-A | 2,4, 6-trisubstituted pyrimidines as Phosphatidylinositol (PI) 3-kinase inhibitors and their use in the treatment of cancer | ASTRAZENECA AB (SE) | 2007-08-08 | — | — | CN | disclosed |
| CN-101010318-A | 2,4, 6-trisubstituted pyrimidines as Phosphatidylinositol (PI) 3-kinase inhibitors and their use in the treatment of cancer | ASTRAZENECA AB (SE) | 2007-08-01 | — | — | CN | disclosed |
| CN-101010317-A | 2, 4,6-trisubstituted pyrimidines as phosphotidylinositol (pi) 3-kinase inhibitors and their use in the treatment of cancer | ASTRAZENECA AB (SE) | 2007-08-01 | — | — | CN | disclosed |
| US-4517379-A | ARTIFICIAL SWEETENER | PFIZER INC. (US) | 1985-05-14 | — | — | US | disclosed |
| EP-0069811-B1 | BRANCHED AMIDES OF L-ASPARTYL-D-AMINO ACID DIPEPTIDES AND COMPOSITIONS THEREOF | PFIZER INC. (US) | 1984-10-24 | — | — | EP | disclosed |
| US-4454328-A | SWEETENERS | PFIZER INC. (US) | 1984-06-12 | — | — | US | disclosed |
| US-4399163-A | ARTIFICIAL SWEETENERS | PFIZER INC. (US) | 1983-08-16 | — | — | US | disclosed |
| EP-0069811-A1 | Branched amides of L-aspartyl-D-amino acid dipeptides and compositions thereof | PFIZER INC. (US) | 1983-01-19 | — | — | EP | disclosed |