Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 2/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | EEF2K | O00418 | 1/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | ROS1 | P08922 | 1/20 | 0.43 |
| ▸ | AKT2 | P31751 | 1/20 | 0.43 |
| ▸ | MATK | P42679 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11408963 | 0.87 | SNCA (0.45) | AURKBAURKACDC7EEF2KPLK4 | |
| SCHEMBL9765207 | 0.87 | AURKB (0.52) | AURKBAURKACDC7EEF2KPLK4 | |
| SCHEMBL10504157 | 0.83 | AURKB (0.52) | AURKBAURKACDC7EEF2KPLK4 | |
| SCHEMBL10796039 | 0.82 | TIMP3 (0.42) | AURKBAURKACDC7EEF2KPLK4 | |
| SCHEMBL11441738 | 0.82 | ALDH1A1 (0.47) | ALDH1A1CA1CA2CA4CA7 | |
| SCHEMBL7894762 | 0.81 | AURKB (0.56) | AURKBAURKACDC7EEF2KPLK4 | |
| Ammonia Solution, Strong SCHEMBL22574486 | 0.81 | ALDH1A1 (0.46) | ALDH1A1CA1CA2CA4CA7 | |
| SCHEMBL22574488 | 0.81 | ALDH1A1 (0.46) | ALDH1A1CA1CA2CA4CA7 | |
| Ammonia Solution, Strong SCHEMBL29466725 | 0.81 | ALDH1A1 (0.46) | ALDH1A1CA1CA2CA4CA7 | |
| SCHEMBL10791619 | 0.80 | TIMP3 (0.47) | AURKBCDC7EEF2KPLK4DYRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4661587-A | Bis 1:2 chromium complexes of disazo and azo or azomethine dyes | CIBA-GEIGY CORPORATION (US) | 1987-04-28 | — | — | US | disclosed |