Propene

Propene

SCHEMBL10796385

C=CC.C=CC.O=C(O)C(O)C(O)C(=O)OCCO

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
HTT P42858 1/20 0.31
CYP2C9 P11712 1/20 0.31
PDE4A P27815 1/20 0.31
GBA1 P04062 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propene SCHEMBL2963067 0.92 TSHR (0.38) TSHRHTT
Ether SCHEMBL2964504 0.92 TSHR (0.38) TSHR
SCHEMBL373841 0.88 TSHR (0.48) TSHRHTTCYP2C9PDE4AGBA1
Propene SCHEMBL6413508 0.86 TSHR (0.41) TSHR
Ether SCHEMBL2962962 0.82 HCAR2 (0.33) TSHR
Glycolic Acid SCHEMBL11314038 0.82 TSHR (0.42) TSHRHTTCYP2C9PDE4AGBA1
Ether SCHEMBL2959187 0.82 ALDH1A1 (0.39) TSHRACHE
Ethylene SCHEMBL2962958 0.82 TSHR (0.34) TSHRHTT
SCHEMBL2963222 0.81 TSHR (0.37) TSHRHTTCYP2C9PDE4AGBA1
Ether SCHEMBL2959250 0.81 ALDH1A1 (0.41) TSHRHTTCYP2C9PDE4AGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4675177-A ALUMINUM-ZIRCONIUM SALTS, LACTATE ESTERS OF LOWER ALKANOLS AMERICAN CYANAMID COMPANY (US) 1987-06-23 US disclosed