Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.57 |
| ▸ | PPARA | Q07869 | 7/20 | 0.57 |
| ▸ | PPARD | Q03181 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10800272 | 0.92 | PPARG (0.54) | PPARGPPARAPPARDKDM4EALDH1A1 | |
| SCHEMBL10796557 | 0.86 | PPARG (0.57) | PPARGPPARAPPARDKDM4EALDH1A1 | |
| SCHEMBL10969883 | 0.85 | PPARG (0.66) | PPARGPPARAPPARDKDM4EALDH1A1 | |
| SCHEMBL11041255 | 0.85 | PPARG (0.53) | PPARGPPARAPPARDKDM4EALDH1A1 | |
| SCHEMBL10798526 | 0.83 | PPARG (0.54) | PPARGPPARAPPARDKDM4EALDH1A1 | |
| SCHEMBL11040046 | 0.83 | MAPT (0.55) | PPARGPPARAPPARDKDM4EALDH1A1 | |
| SCHEMBL11037265 | 0.83 | MAPT (0.61) | PPARGPPARAPPARDKDM4EALDH1A1 | |
| SCHEMBL11039275 | 0.83 | PPARG (0.52) | PPARGPPARAPPARDKDM4EALDH1A1 | |
| SCHEMBL11040888 | 0.83 | ALDH1A1 (0.54) | PPARGPPARAPPARDKDM4EALDH1A1 | |
| SCHEMBL11039737 | 0.83 | PPARG (0.52) | PPARGPPARAPPARDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711879-A | IMMUNO-MODULATING ACTIVITY | CIBA-GEIGY CORPORATION (US) | 1987-12-08 | — | — | US | claimed |
| US-4640911-A | IMMUNOSTIMULANTS, VIRICIDES SUCH AS HERPES SIMPLEX | CIBA-GEIGY CORPORATION (US) | 1987-02-03 | — | — | US | claimed |
| EP-0163286-A2 | Acylated sugars, method for their preparation and their use | CIBA-GEIGY AG (CH) | 1985-12-04 | — | — | EP | claimed |
| US-4711879-A | IMMUNO-MODULATING ACTIVITY | CIBA-GEIGY CORPORATION (US) | 1987-12-08 | — | — | US | disclosed |
| US-4640911-A | IMMUNOSTIMULANTS, VIRICIDES SUCH AS HERPES SIMPLEX | CIBA-GEIGY CORPORATION (US) | 1987-02-03 | — | — | US | disclosed |