Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.66 |
| ▸ | PPARA | Q07869 | 7/20 | 0.66 |
| ▸ | PPARD | Q03181 | 7/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10797270 | 0.93 | PPARG (0.61) | PPARGPPARAPPARDPTGS2MAPT | |
| SCHEMBL10801302 | 0.86 | PPARD (0.61) | PPARGPPARAPPARDPTGS2MAPT | |
| SCHEMBL10965032 | 0.86 | HRH3 (0.58) | PPARGPPARAPTGS2MAPTALDH1A1 | |
| SCHEMBL10796557 | 0.85 | PPARG (0.57) | PPARGPPARAPPARDPTGS2MAPT | |
| SCHEMBL10796552 | 0.85 | PPARG (0.57) | PPARGPPARAPPARDPTGS2MAPT | |
| SCHEMBL11752001 | 0.83 | PPARD (0.58) | PPARGPPARAPPARDPTGS2MAPT | |
| SCHEMBL11754768 | 0.83 | PPARD (0.58) | PPARGPPARAPPARDPTGS2MAPT | |
| SCHEMBL11040651 | 0.82 | PPARD (0.56) | PPARGPPARAPPARDPTGS2MAPT | |
| SCHEMBL10798526 | 0.82 | PPARG (0.54) | PPARGPPARAPPARDPTGS2MAPT | |
| SCHEMBL10800272 | 0.82 | PPARG (0.54) | PPARGPPARAPPARDPTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0137426-A2 | 2-Mercaptothiazole derivatives, process for their preparation and utilization of 2-mercaptothiazole derivatives in pharmaceutical compounds | BAYER AG (DE) | 1985-04-17 | — | — | EP | disclosed |