Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10803243 | 0.85 | MAPK1 (0.48) | TDP1GAAALDH1A1MAPK1HTT | |
| SCHEMBL11735174 | 0.83 | TDP1 (0.53) | ATMTDP1ALDH1A1MAPK1HTT | |
| SCHEMBL10796809 | 0.82 | ALDH1A1 (0.44) | ATMTDP1GAAALDH1A1MAPK1 | |
| SCHEMBL10801689 | 0.82 | HRAS (0.49) | ATMTDP1GAAALDH1A1MAPK1 | |
| SCHEMBL10799904 | 0.78 | MAPT (0.52) | TDP1GAAALDH1A1MAPK1HTT | |
| SCHEMBL10801744 | 0.77 | MAPK1 (0.53) | TDP1GAAALDH1A1MAPK1HTT | |
| SCHEMBL3602490 | 0.76 | ATM (0.51) | ATMTDP1GAAALDH1A1MAPK1 | |
| SCHEMBL10797159 | 0.76 | MAPK1 (0.47) | TDP1ALDH1A1MAPK1HTTNPC1 | |
| SCHEMBL11387513 | 0.76 | TDP1 (0.47) | ATMTDP1ALDH1A1MAPK1HTT | |
| SCHEMBL11137481 | 0.75 | ATM (0.44) | ATMTDP1GAAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670596-A | INSECTICIDE, MITICIDE | ELI LILLY AND COMPANY (US) | 1987-06-02 | — | — | US | disclosed |