Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | BHMT | Q93088 | 5/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.34 |
| ▸ | KDM4A | O75164 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.34 |
| ▸ | TET3 | O43151 | 1/20 | 0.34 |
| ▸ | ARG1 | P05089 | 1/20 | 0.34 |
| ▸ | ARG2 | P78540 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10800375 | 0.86 | LMNA (0.64) | LMNAKMT2AHSD17B10TDP1TSHR | |
| SCHEMBL9087634 | 0.83 | LMNA (0.52) | LMNAKMT2AHSD17B10TDP1TSHR | |
| SCHEMBL4453453 | 0.83 | LMNA (0.93) | LMNAKMT2AHSD17B10TDP1TSHR | |
| SCHEMBL13231021 | 0.82 | LMNA (0.42) | LMNAKMT2AHSD17B10TDP1TSHR | |
| E388 SCHEMBL28962323 | 0.80 | LMNA (1.00) | LMNAKMT2AHSD17B10TDP1TSHR | |
| E388 SCHEMBL28696 | 0.80 | LMNA (1.00) | LMNAKMT2AHSD17B10TDP1TSHR | |
| SCHEMBL13160468 | 0.78 | LMNA (0.46) | LMNAKMT2AHSD17B10TDP1TSHR | |
| SCHEMBL16715949 | 0.77 | LMNA (0.56) | LMNAKMT2AHSD17B10TDP1TSHR | |
| E388 SCHEMBL341724 | 0.77 | LMNA (0.93) | LMNAKMT2AHSD17B10TDP1TSHR | |
| E388 SCHEMBL9715444 | 0.77 | LMNA (0.93) | LMNAKMT2AHSD17B10TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4695535-A | ACYCLIC THIOETHER, SILVER HALIDE CRYSTAL GROWTH | EASTMAN KODAK COMPANY (US) | 1987-09-22 | — | — | US | disclosed |