Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1076424 | 0.86 | TSHR (0.51) | TSHRAVPR2AVPR1ALMNAKDM4E | |
| SCHEMBL1078087 | 0.82 | NOTUM (0.47) | — | |
| SCHEMBL16935851 | 0.77 | AVPR2 (0.51) | TSHRAVPR2AVPR1AKDM4EALDH1A1 | |
| SCHEMBL1076549 | 0.76 | HTR2A (0.46) | L3MBTL1 | |
| SCHEMBL28674639 | 0.70 | ALDH1A1 (0.48) | TSHRLMNAKDM4EALDH1A1THRB | |
| SCHEMBL22289852 | 0.69 | L3MBTL1 (0.53) | TSHRAVPR2AVPR1AKDM4EALDH1A1 | |
| SCHEMBL28081745 | 0.69 | AVPR2 (0.49) | TSHRAVPR2AVPR1AKDM4EALDH1A1 | |
| SCHEMBL31532182 | 0.69 | AVPR2 (0.55) | TSHRAVPR2AVPR1AKDM4EALDH1A1 | |
| SCHEMBL21354520 | 0.68 | GAA (0.56) | TSHRAVPR2AVPR1ALMNAKDM4E | |
| SCHEMBL16063426 | 0.68 | CNR1 (0.54) | TSHRLMNAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011005052-A2 | NOVEL ARYLPIPERAZINE-CONTAINING IMIDAZOLE 4-CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | GREEN GROSS CORPORATION (KR) | 2011-01-13 | — | — | WO | disclosed |