SCHEMBL10797992

SCHEMBL10797992

CCCCc1ccc(-c2ccccc2N=Nc2ccc(N=Nc3ccc(O)cc3)c3ccccc23)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
CYP3A4 P08684 3/20 0.41
ESR1 P03372 2/20 0.41
ADRA2A P08913 2/20 0.41
ADORA3 P0DMS8 2/20 0.41
TACR2 P21452 2/20 0.41
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HSD17B10 Q99714 2/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
SHBG P04278 1/20 0.41
TP53 P04637 1/20 0.41
HSPD1 P10809 1/20 0.41
ADRB3 P13945 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10792893 0.82 NPC1 (0.44) CASP3SENP8SENP7SENP6ALDH1A1
SCHEMBL10798765 0.81 L3MBTL1 (0.48) CYP3A4ALDH1A1KDM4ELMNAMEN1
SCHEMBL29078081 0.78 CASP3 (0.53) CASP3SENP8SENP7SENP6ALDH1A1
SCHEMBL8804353 0.78 MAPT (0.39) PTPN1MEN1KMT2ADHODHMAPT
SCHEMBL508936 0.78 ESR1 (0.66) CYP3A4ESR1ADRA2AADORA3TACR2
SCHEMBL20579978 0.78 ESR1 (0.66) CYP3A4ESR1ADRA2AADORA3TACR2
SCHEMBL508935 0.78 ESR1 (0.66) CYP3A4ESR1ADRA2AADORA3TACR2
SCHEMBL20579977 0.78 ESR1 (0.66) CYP3A4ESR1ADRA2AADORA3TACR2
SCHEMBL8804349 0.78 MEN1 (0.44) MEN1KMT2A
SCHEMBL17323000 0.77 MEN1 (0.40) CYP3A4ALDH1A1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4676923-A DISAZO DYES KABUSHIKI KAISHA NIPPON KANKO SHIKISO KENKYUSHO (JP) 1987-06-30 US disclosed