Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10655994 | 0.90 | GAA (0.52) | GAARAB9AALDH1A1MAPTHTT | |
| SCHEMBL9733367 | 0.84 | MME (0.62) | GAARAB9AMAPTLMNASMN1; SMN2 | |
| SCHEMBL7280394 | 0.84 | MME (0.62) | GAARAB9AMAPTLMNASMN1; SMN2 | |
| SCHEMBL7280398 | 0.84 | MME (0.62) | GAARAB9AMAPTLMNASMN1; SMN2 | |
| SCHEMBL22604666 | 0.77 | GAA (0.73) | GAARAB9AACACBPPARGITGB3 | |
| SCHEMBL3370856 | 0.77 | KMT2A (0.60) | GAARAB9AALDH1A1MAPTHTT | |
| SCHEMBL3370862 | 0.77 | KMT2A (0.60) | GAARAB9AALDH1A1MAPTHTT | |
| SCHEMBL6025269 | 0.77 | KMT2A (0.60) | GAARAB9AALDH1A1MAPTHTT | |
| SCHEMBL21015668 | 0.77 | ACACB (0.51) | GAARAB9AACACBMMEITGB3 | |
| SCHEMBL19465105 | 0.77 | ACACB (0.51) | GAARAB9AACACBMMEITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4668796-A | Racemates of optically active bicyclic imino-alpha-carboxylic esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-05-26 | — | — | US | disclosed |