Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6025269 | 1.00 | KMT2A (0.60) | KMT2AMEN1NPC1NPSR1POLB | |
| SCHEMBL3370862 | 1.00 | KMT2A (0.60) | KMT2AMEN1NPC1NPSR1POLB | |
| SCHEMBL10735346 | 0.86 | KMT2A (0.48) | KMT2AMEN1NPC1MAPTLMNA | |
| SCHEMBL8622468 | 0.86 | KMT2A (0.53) | KMT2AMEN1NPC1NPSR1POLB | |
| SCHEMBL7097431 | 0.86 | KMT2A (0.53) | KMT2AMEN1NPC1NPSR1POLB | |
| SCHEMBL28547510 | 0.86 | KMT2A (0.53) | KMT2AMEN1NPC1NPSR1POLB | |
| SCHEMBL10706582 | 0.85 | TSHR (0.53) | KMT2AMEN1NPC1NPSR1POLB | |
| SCHEMBL27858522 | 0.85 | KMT2A (0.58) | KMT2AMEN1NPC1NPSR1POLB | |
| Trifluoroacetic Acid SCHEMBL9864408 | 0.80 | KMT2A (0.42) | KMT2AMEN1NPSR1POLBMAPT | |
| SCHEMBL25275491 | 0.80 | KMT2A (0.63) | KMT2AMEN1NPC1NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1679303-B1 | Process for preparing 1-alkoxycarbonyl-3-phenylpropyl derivative | KANEKA CORP (JP) | 2010-09-15 | — | — | EP | disclosed |
| EP-1284957-B1 | PURIFICATION METHOD OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE | KANEKA CORP (JP) | 2008-05-07 | — | — | EP | disclosed |
| EP-1679303-A1 | Process for preparing 1-alkoxycarbonyl-3-phenylpropyl derivative | Kaneka Corporation (JP) | 2006-07-12 | — | — | EP | disclosed |
| US-7071349-B2 | Purification method of N-(1(S)-ethoxycarbonyl-3-phenylpropyl)-L-alanine | KANAKA CORPORATION (JP) | 2006-07-04 | — | — | US | disclosed |
| EP-0903337-B1 | PROCESS FOR THE PREPARATION OF 1-ALKOXYCARBONYL-3-PHENYLPROPYL DERIVATIVES | KANEKA CORP (JP) | 2006-04-12 | — | — | EP | disclosed |
| EP-1284957-A4 | PURIFICATION METHOD OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE | KANEKA CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| US-20030162991-A1 | Purification method of n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanine | KANEKA CORPORATION (JP) | 2003-08-28 | — | — | US | disclosed |
| EP-1284957-A1 | PURIFICATION METHOD OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE | KANEKA CORPORATION (JP) | 2003-02-26 | — | — | EP | disclosed |
| WO-2002074728-A1 | PURIFICATION METHOD OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE | KANEKA CORPORATION (JP) | 2002-09-26 | — | — | WO | disclosed |
| US-6118010-A | CATALYTIC REDUCTION OF THE 1-ALKOXYCARBONYL-3-OXO-3-PHENYLPROPYL DERIVATIVE | KANEKA CORPORATION (JP) | 2000-09-12 | — | — | US | disclosed |
| US-4614805-A | Bicyclic amino acids as intermediates in the preparation of tricyclic amino acids and processes for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-30 | — | — | US | disclosed |
| US-4558065-A | Derivatives of tricyclic aminoacids, processes for their preparation, agents containing these compounds and their use, and new bicyclic aminoacids as intermediates and processes for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-12-10 | — | — | US | disclosed |
| EP-0150263-A1 | Derivatives of cis, endo-2-azabicyclo-[3.3.0]-octane-3-carboxylic acid, process for their preparation, medicaments containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-08-07 | — | — | EP | disclosed |
| EP-0116276-A2 | Derivatives of spirocyclic amino-acids, their process of preparation, agents containing them, and their use, as well as spirocyclic amino-acids as intermediaries and their process of preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-08-22 | — | — | EP | disclosed |
| EP-0111873-A1 | Derivatives of cis, endo-2-azabicyclo-(5.3.0)-decane-3-carboxylic acid, process for their preparation, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-06-27 | — | — | EP | disclosed |
| EP-0109020-A2 | Derivatives from tricyclic amino acids, process for their preparation, compounds containing them and their use, as well as bicyclic amino acids as intermediates and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-05-23 | — | — | EP | disclosed |
| EP-0105102-A1 | 2-Aza-bicyclo(2,2,2)-octane-3-carboxylic-acid derivatives, process for their preparation, pharmaceutical preparations containing them and their application, and 2-aza-bicyclo(2,2,2)-octane-3-carboxylic acid as an intermediate and its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-04-11 | — | — | EP | disclosed |
| EP-0090362-A2 | Derivatives of cycloalka(c)pyrrole-carboxylic acids, process for their preparation, agents containing them and their use, as well as cycloalka(c)pyrrole-carboxylic acids as intermediates, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-10-05 | — | — | EP | disclosed |
| EP-0089637-A2 | Bicyclic amino acid derivatives, process for their preparation, agents containing them and their application, bicyclic amino acids as intermediates, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-09-28 | — | — | EP | disclosed |
| EP-0079022-A2 | Derivatives of cis, endo-2-azabicyclo-(3.3.0)-octane-3-carboxylic acid, process for their preparation, medicines containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-05-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162991-A1 | Purification method of n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanine | ANPEP, NPEPPS, ADH1A | KMT2A 3766/4885MEN1 2084/4885NPC1 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.