Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.47 |
| ▸ | REN | P00797 | 3/20 | 0.44 |
| ▸ | FAP | Q12884 | 2/20 | 0.44 |
| ▸ | PREP | P48147 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PEPD | P12955 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10799358 | 0.86 | ACE (0.54) | ACERENLMNAHSD17B10CYP2C19 | |
| SCHEMBL28913603 | 0.83 | FAP (0.61) | ACERENFAPPREPDPP4 | |
| SCHEMBL10797994 | 0.79 | ACE (0.53) | ACERENLMNAHSD17B10CYP2C19 | |
| SCHEMBL13246638 | 0.79 | ACE (0.53) | ACEREN | |
| SCHEMBL15756757 | 0.79 | ACE (0.53) | ACEREN | |
| SCHEMBL10763041 | 0.78 | REN (0.53) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL17202450 | 0.78 | ACE (0.49) | ACERENFAPPREPDPP4 | |
| SCHEMBL11413122 | 0.77 | ACE (0.56) | ACERENLMNAHSD17B10CYP2C19 | |
| SCHEMBL7376055 | 0.77 | ACE (0.56) | ACERENLMNAHSD17B10CYP2C19 | |
| SCHEMBL29363134 | 0.77 | ACE (0.52) | ACERENPREPLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4684660-A | Mercaptoacyldepeptides | E. R. SQUIBB & SONS, INC. (US) | 1987-08-04 | — | — | US | disclosed |