SCHEMBL10799196

SCHEMBL10799196

O=[N+]([O-])Nc1c(Br)cc(Cl)cc1I

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
NPBWR1 P48145 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10801541 0.87 ALDH1A1 (0.39) ALDH1A1TSHRNPBWR1
SCHEMBL10801949 0.87 ALDH1A1 (0.39) ALDH1A1TSHRNPBWR1
SCHEMBL10801328 0.82 TSHR (0.44) ALDH1A1TSHR
SCHEMBL10796285 0.82 MEN1 (0.30)
SCHEMBL10800640 0.82 MEN1 (0.31)
SCHEMBL10796706 0.76 NMT1 (0.35)
SCHEMBL10801954 0.76 MEN1 (0.33)
SCHEMBL10800358 0.76 MEN1 (0.33)
SCHEMBL11570409 0.71 CYP1A2 (0.33) ALDH1A1TSHR
SCHEMBL10796213 0.71 NMT1 (0.37) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0003880-A1 Substituted phenylnitramines with plant growth regulating properties AMERICAN CYANAMID COMPANY (US) 1979-09-05 EP claimed
US-4643755-A APPLYING SUBSTITUTED PHENYL NITRAMINE AMERICAN CYANAMID COMPANY (US) 1987-02-17 US disclosed
EP-0003880-A1 Substituted phenylnitramines with plant growth regulating properties AMERICAN CYANAMID COMPANY (US) 1979-09-05 EP disclosed