Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | BRS3 | P32247 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11802122 | 0.81 | CSNK2A1 (0.55) | CYP2A6SLC6A2SLC6A4SLC6A3MMP2 | |
| SCHEMBL11807188 | 0.81 | GRIA4 (0.55) | HCAR2GRM2MMP2 | |
| SCHEMBL11823728 | 0.80 | MAOB (0.54) | MAOBCYP2A6HCAR2MMEMMP2 | |
| SCHEMBL11832648 | 0.80 | MAOB (0.54) | MAOBCYP2A6HCAR2GRM2HSD11B1 | |
| SCHEMBL11833689 | 0.80 | MAOB (0.47) | MAOBHCAR2GRM2MMEMMP2 | |
| SCHEMBL4629521 | 0.79 | MAOB (0.70) | MAOBCYP2A6HCAR2GRM2HSD11B1 | |
| SCHEMBL10585872 | 0.79 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL425971 | 0.79 | MMP12 (0.59) | MMEMMP2MMP9MMP12MMP13 | |
| SCHEMBL11832645 | 0.79 | MAOB (0.56) | MAOBCYP2A6HCAR2GRM2MME | |
| SCHEMBL11829433 | 0.79 | MAOB (0.49) | MAOBCYP2A6HCAR2GRM2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4714789-A | AND OBESITY | P. F. MEDICAMENT (FR) | 1987-12-22 | — | — | US | claimed |
| US-4714789-A | AND OBESITY | P. F. MEDICAMENT (FR) | 1987-12-22 | — | — | US | disclosed |
| US-3950427-A | ANTIINFLAMMATORY, ANTIPYRETIC | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |