Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11834955 | 0.88 | MAOB (0.47) | MAOBHCAR2MMEGRM2ITGB1 | |
| SCHEMBL11823728 | 0.81 | MAOB (0.54) | MAOBHCAR2MMEITGB1ITGA4 | |
| SCHEMBL11832645 | 0.80 | MAOB (0.56) | MAOBHCAR2MMEGRM2ITGB1 | |
| SCHEMBL10799345 | 0.80 | MAOB (0.58) | MAOBHCAR2MMEGRM2MMP2 | |
| SCHEMBL11829433 | 0.80 | MAOB (0.49) | MAOBHCAR2MMEGRM2ITGB1 | |
| SCHEMBL11824437 | 0.79 | MAOB (0.48) | MAOBHCAR2MMEGRM2SMN1; SMN2 | |
| SCHEMBL11846787 | 0.78 | KEAP1 (0.43) | MMESMN1; SMN2TSHR | |
| SCHEMBL11845154 | 0.75 | AKR1C3 (0.41) | MMESMN1; SMN2TSHR | |
| SCHEMBL11845029 | 0.74 | TSHR (0.40) | MMESMN1; SMN2TSHR | |
| SCHEMBL11846461 | 0.74 | KEAP1 (0.44) | MMESMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |