Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 12/20 | 0.67 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10801148 | 0.94 | KCNK3 (0.69) | KCNK3CREBBP | |
| SCHEMBL14784434 | 0.88 | KCNK3 (0.80) | KCNK3CREBBP | |
| SCHEMBL10817914 | 0.87 | KCNK3 (0.70) | KCNK3 | |
| SCHEMBL10805647 | 0.86 | KCNK3 (0.68) | KCNK3 | |
| SCHEMBL10800553 | 0.86 | — | — | |
| SCHEMBL10805706 | 0.85 | KCNK3 (0.67) | KCNK3 | |
| SCHEMBL10801107 | 0.83 | KCNK3 (0.86) | KCNK3 | |
| SCHEMBL10799759 | 0.80 | CREBBP (0.72) | KCNK3CREBBP | |
| SCHEMBL14791429 | 0.80 | KCNK3 (1.00) | KCNK3CREBBP | |
| SCHEMBL10806622 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086422-B1 | PHARMACOLOGICALLY ACTIVE PYRAZOLO(4,3-C)PYRIDINES | GRUPPO LEPETIT S.p.A. (IT) | 1987-09-30 | — | — | EP | disclosed |
| US-4500525-A | CARDIOTONIC, HYPOTENSIVE, NEUROLEPTIC, ANALGESIC, ANTIINFLAMMATORYAGENTS, AND CENTRAL NERVOUS SYSTEM DEPRESSANTS | GRUPPO LEPETIT S.P.A. (IT) | 1985-02-19 | — | — | US | disclosed |