Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10795123 | 0.90 | MEN1 (0.49) | MEN1KMT2APOLBMCL1CCR1 | |
| SCHEMBL9762899 | 0.85 | GAA (0.48) | POLBCCR1TDP1MAPTTSHR | |
| SCHEMBL7824863 | 0.83 | POLB (0.45) | MEN1KMT2APOLBCCR1MAPT | |
| SCHEMBL12226555 | 0.81 | KMT2A (0.44) | MEN1KMT2AMAPTTSHRCA12 | |
| SCHEMBL11113640 | 0.78 | MEN1 (0.49) | MEN1KMT2APOLBCCR1TDP1 | |
| SCHEMBL11315772 | 0.77 | MEN1 (0.45) | MEN1KMT2APOLBMCL1TDP1 | |
| SCHEMBL11112106 | 0.76 | CCR1 (0.46) | MEN1KMT2APOLBMCL1CCR1 | |
| SCHEMBL10795105 | 0.76 | MEN1 (0.46) | MEN1KMT2AMAPTCA12CA1 | |
| SCHEMBL8968894 | 0.76 | KMT2A (0.42) | MEN1KMT2AMAPTTSHRPKM | |
| SCHEMBL8970364 | 0.76 | KMT2A (0.42) | MEN1KMT2AMAPTTSHRPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4652634-A | Water-soluble monoazo compounds containing a N-(sulfoalkyl)-aniline coupling component and a fiber-reactive group of the vinylsulfonyl series in the phenyl or benzothiazole diazo component, suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-24 | — | — | US | disclosed |
| EP-0051808-B1 | WATER-SOLUBLE MONOAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-04 | — | — | EP | disclosed |
| US-4430259-A | Water-soluble disazo compounds suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-07 | — | — | US | disclosed |
| EP-0051807-A2 | Water-soluble disazo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-05-19 | — | — | EP | disclosed |
| EP-0051808-A2 | Water-soluble monoazo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-05-19 | — | — | EP | disclosed |