Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.44 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761992 | 0.91 | GAA (0.50) | GAAPOLBALDH1A1LMNATSHR | |
| SCHEMBL10799697 | 0.85 | MEN1 (0.46) | GAAPOLBTSHRCCR1TDP1 | |
| SCHEMBL2743946 | 0.84 | CYP3A4 (0.54) | GAAGUCY1A1GUCY1B1ALDH1A1LMNA | |
| SCHEMBL10126545 | 0.82 | GUCY1A1 (0.59) | GAAPOLBGUCY1A1GUCY1B1ALDH1A1 | |
| SCHEMBL25396737 | 0.81 | CYP3A4 (0.54) | GAAGUCY1A1GUCY1B1ALDH1A1LMNA | |
| SCHEMBL7824863 | 0.81 | POLB (0.45) | GAAPOLBALDH1A1LMNACCR1 | |
| SCHEMBL7657031 | 0.80 | GAA (0.50) | GAAPOLBGUCY1A1GUCY1B1ALDH1A1 | |
| SCHEMBL9852005 | 0.78 | MAPT (0.58) | GAAPOLBALDH1A1TDP1MAPT | |
| SCHEMBL2743807 | 0.77 | CYP3A4 (0.50) | GUCY1A1GUCY1B1LMNATSHR | |
| SCHEMBL30575034 | 0.77 | KMT2A (0.42) | GAAGUCY1A1GUCY1B1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003052-A | Monoazo fiber reactive dye for cellulose, polyamides, wool, silk, polyurethanes and leather | CIBA-GEIGY CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |
| US-4652634-A | Water-soluble monoazo compounds containing a N-(sulfoalkyl)-aniline coupling component and a fiber-reactive group of the vinylsulfonyl series in the phenyl or benzothiazole diazo component, suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-24 | — | — | US | disclosed |
| EP-0208655-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1987-01-14 | — | — | EP | disclosed |
| EP-0051808-B1 | WATER-SOLUBLE MONOAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-04 | — | — | EP | disclosed |
| US-4430259-A | Water-soluble disazo compounds suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-07 | — | — | US | disclosed |
| EP-0051808-A2 | Water-soluble monoazo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-05-19 | — | — | EP | disclosed |