Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5966531 | 1.00 | SLC1A3 (0.42) | SLC1A3SLC1A2SLC1A1CYP1A2MEN1 | |
| SCHEMBL6506673 | 0.83 | SLC1A3 (0.41) | SLC1A3SLC1A2SLC1A1CYP1A2MEN1 | |
| SCHEMBL7270008 | 0.83 | SLC1A3 (0.41) | SLC1A3SLC1A2SLC1A1CYP1A2MEN1 | |
| SCHEMBL17786890 | 0.80 | SLC1A3 (0.42) | SLC1A3SLC1A2SLC1A1CYP1A2MEN1 | |
| SCHEMBL1486231 | 0.78 | LAP3 (0.42) | CYP1A2MEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10390137 | 0.76 | CETP (0.40) | TSHRALDH1A1PKM | |
| SCHEMBL10605773 | 0.76 | SLC6A2 (0.42) | CYP2D6EPHX1SRRPKMCTRB1 | |
| SCHEMBL3276722 | 0.74 | TSHR (0.52) | SLC1A3SLC1A2SLC1A1CYP1A2MEN1 | |
| SCHEMBL2673956 | 0.74 | SLC6A2 (0.45) | SLC1A3SLC1A2SLC1A1CYP1A2MEN1 | |
| SCHEMBL2485067 | 0.74 | SLC1A3 (0.43) | SLC1A3SLC1A2SLC1A1CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230242-A2 | Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-29 | — | — | EP | disclosed |