Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 4/20 | 0.68 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10814988 | 0.99 | KCNK3 (0.67) | KCNK3HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL10805648 | 0.95 | KCNK3 (0.60) | KCNK3HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL10805772 | 0.88 | KCNK3 (0.53) | KCNK3HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL10805409 | 0.87 | HTR1A (0.54) | KCNK3HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL10799600 | 0.87 | HTR1A (0.53) | HTR1ADRD2HTR2AHTR7HRH1 | |
| SCHEMBL14786430 | 0.87 | KCNK3 (0.72) | KCNK3 | |
| SCHEMBL10803941 | 0.85 | DRD2 (0.56) | KCNK3HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL10805187 | 0.85 | KCNK3 (0.61) | KCNK3 | |
| SCHEMBL10805153 | 0.83 | KCNK3 (0.63) | KCNK3 | |
| SCHEMBL10818479 | 0.83 | KCNK3 (0.58) | KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086422-B1 | PHARMACOLOGICALLY ACTIVE PYRAZOLO(4,3-C)PYRIDINES | GRUPPO LEPETIT S.p.A. (IT) | 1987-09-30 | — | — | EP | disclosed |