Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10810205 | 0.82 | MEN1 (0.82) | MAPTMEN1KMT2APSMB8NPC1 | |
| SCHEMBL9468453 | 0.80 | MAPT (0.67) | MAPTMEN1KMT2APSMB8NPC1 | |
| SCHEMBL9187037 | 0.80 | KDM1A (0.53) | MAPTMEN1KMT2AMAOBMAOA | |
| SCHEMBL7703302 | 0.77 | MEN1 (0.82) | MAPTMEN1KMT2APSMB8HSD17B10 | |
| SCHEMBL11158833 | 0.75 | MAOB (0.54) | MAPTMEN1KMT2AMAOBHSD17B10 | |
| SCHEMBL1258329 | 0.74 | MAOB (0.50) | MAPTMEN1KMT2AMAOBMAOA | |
| SCHEMBL483262 | 0.72 | MEN1 (1.00) | MAPTMEN1KMT2ATSHRNPC1 | |
| Dibenzofuran SCHEMBL28066911 | 0.72 | MEN1 (1.00) | MAPTMEN1KMT2ATSHRNPC1 | |
| SCHEMBL11156762 | 0.72 | MAOB (0.50) | MAPTMEN1KMT2AMAOBPSMB8 | |
| SCHEMBL3072969 | 0.71 | MEN1 (0.67) | MAPTMEN1KMT2AMAOBPSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110831-B1 | THIOXANTHONES SUBSTITUTED BY ALPHA-AMINOALKYL GROUPS | CIBA-GEIGY AG (CH) | 1987-03-04 | — | — | EP | disclosed |
| EP-0110831-A1 | Thioxanthones substituted by alpha-aminoalkyl groups | CIBA-GEIGY AG (CH) | 1984-06-13 | — | — | EP | disclosed |