Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10800976 | 1.00 | HDAC6 (0.52) | HDAC6DDB1CRBNMAPTGRM2 | |
| SCHEMBL9536800 | 0.92 | DDB1 (0.55) | HDAC6DDB1CRBNMAPTGRM2 | |
| Hydrochloric Acid SCHEMBL29232383 | 0.91 | DDB1 (0.54) | HDAC6DDB1CRBNMAPTGRM2 | |
| Hydrochloric Acid SCHEMBL30918533 | 0.91 | DDB1 (0.54) | HDAC6DDB1CRBNMAPTGRM2 | |
| SCHEMBL14685201 | 0.83 | DDB1 (0.58) | HDAC6DDB1CRBNMAPTGRM2 | |
| SCHEMBL8231533 | 0.79 | LMNA (0.55) | DDB1CRBNMAPTALDH1A1LMNA | |
| SCHEMBL9537925 | 0.79 | HTR2B (0.58) | HDAC6DDB1CRBNGRM2ALDH1A1 | |
| SCHEMBL1532834 | 0.78 | MAPT (0.54) | HDAC6DDB1CRBNMAPTGRM2 | |
| SCHEMBL9537264 | 0.77 | GBA1 (0.46) | LMNANPY1RGBA1 | |
| SCHEMBL8232758 | 0.76 | GRM2 (0.64) | HDAC6DDB1CRBNMAPTGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4695575-A | ANTIHISTAMINES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1987-09-22 | — | — | US | disclosed |