SCHEMBL10800984

SCHEMBL10800984

CN(C)C(=O)CSCC(=O)N(C)C

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.48
GAA P10253 1/20 0.42
ALDH1A1 P00352 6/20 0.42
CYP2D6 P10635 1/20 0.40
HIF1A Q16665 1/20 0.40
TSHR P16473 2/20 0.35
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA4 P43681 1/20 0.34
HSD17B10 Q99714 3/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NFKB1 P19838 1/20 0.32
THPO P40225 1/20 0.32
MAPT P10636 1/20 0.32
APEX1 P27695 1/20 0.32
PMP22 Q01453 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9698273 0.87 HTT (0.42) HTTGAAALDH1A1CYP2D6HIF1A
SCHEMBL13939437 0.86
SCHEMBL10703997 0.81 GAA (0.42) HTTGAAALDH1A1CYP2D6TSHR
SCHEMBL4740333 0.79
SCHEMBL9696853 0.78 HTT (0.40) HTTGAAALDH1A1
SCHEMBL18782792 0.77
SCHEMBL4740331 0.77
SCHEMBL9697831 0.75 GAA (0.38) HTTGAAALDH1A1TSHRCHRNB2
SCHEMBL24868723 0.73 CHRNB2 (0.39) HTTGAAALDH1A1CHRNB2CHRNB4
SCHEMBL23690531 0.71 LMNA (0.49) HTTGAAALDH1A1CYP2D6HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4713438-A Amide and/or imide containing polymers and monomers for the preparation thereof AMOCO CORPORATION (US) 1987-12-15 US disclosed
US-4528373-A Vinylacetylene-terminated polyimide derivatives PLASTICS ENGINEERING COMPANY (US) 1985-07-09 US disclosed
US-4528349-A Polymerization products of vinylacetylene-terminated polyimide derivatives PLASTICS ENGINEERING COMPANY (US) 1985-07-09 US disclosed
US-4520198-A A DIEL-ALDER ADDITION PRODUCT WITH DIENOPHILE PLASTICS ENGINEERING COMPANY (US) 1985-05-28 US disclosed
US-4517363-A Vinylacetylene-terminated polyimide derivatives PLASTICS ENGINEERING COMPANY (US) 1985-05-14 US disclosed
US-4517354-A PROTECTIVE COATINGS PLASTICS ENGINEERING COMPANY (US) 1985-05-14 US disclosed
US-4517364-A CROSSLINKING POYLMERS, DIELS-ALDER ADDITION REACTION PLASTICS ENGINEERING COMPANY (US) 1985-05-14 US disclosed
US-4451402-A MOLDING MATERIALS; VARNISHES; COATINGS PLASTICS ENGINEERING COMPANY (US) 1984-05-29 US disclosed
US-4451669-A ACETYLENIC POLYHEMIAMIC ACIDS PLASTICS ENGINEERING COMPANY (US) 1984-05-29 US disclosed
US-4438280-A END GROUPS FOR POLYIMIDES PLASTICS ENGINEERING COMPANY (US) 1984-03-20 US disclosed
US-4277583-A POLYEPOXIDES OF IMPROVED WORKABILITY AND HEAT RESISTANCE PLASTICS ENGINEERING COMPANY (US) 1981-07-07 US disclosed
US-4168367-A BY-PRODUCT INHIBITION, CROSSLINKING PLASTICS ENGINEERING COMPANY (US) 1979-09-18 US disclosed
US-4168360-A CROSSLINKED, INSOLUBLE, INFUSIBLE COATINGS AND MOLDING MATERIALS PLASTICS ENGINEERING COMPANY (US) 1979-09-18 US disclosed
US-4168366-A ESTERIFICATION WITH UNSATURATED ALCOHOL PLASTICS ENGINEERING COMPANY (US) 1979-09-18 US disclosed
US-4166168-A POLYMERIZATION PRODUCTS OF ACETYLENE-TERMINATED POLYIMIDE DERIVATIVES PLASTICS ENGINEERING COMPANY (US) 1979-08-28 US disclosed
US-4131730-A Modified polyamic acid from aminophthalic acid anhydride and dianhydride ALELIO GAETANO F D 1978-12-26 US disclosed
US-4064113-A POLYAMIC ACID ALELIO GAETANO F D 1977-12-20 US disclosed
US-4026904-A Aromatic epoxy-terminated polyimides UNIVERSITY OF NOTRE DAME (US) 1977-05-31 US disclosed
US-3996196-A Polyimide-metallo-phthalocyanines and their preparation UNIVERSITY OF NOTRE DAME DU LAC (US) 1976-12-07 US disclosed
US-3979416-A REFRIGERATED WATER, PRECIPITATION ALELIO GAETANO F D 1976-09-07 US disclosed