Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cefprozil Anhydrous, (E)-. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 1.00 |
| ▸ | DRD2 | P14416 | 1/20 | 1.00 |
| ▸ | DRD3 | P35462 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 8/20 | 0.98 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.98 |
| ▸ | MEN1 | O00255 | 5/20 | 0.98 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.75 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.75 |
| ▸ | ESR1 | P03372 | 1/20 | 0.75 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.75 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | BLM | P54132 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cefprozil Anhydrous, (E)- SCHEMBL16072814 | 1.00 | PTGS2 (1.00) | PTGS2DRD2DRD3MAPTALDH1A1 | |
| Cefprozil Anhydrous, (E)- SCHEMBL9177544 | 1.00 | PTGS2 (1.00) | PTGS2DRD2DRD3MAPTALDH1A1 | |
| Cefprozil Anhydrous, (E)- SCHEMBL18814837 | 1.00 | PTGS2 (1.00) | PTGS2DRD2DRD3MAPTALDH1A1 | |
| Cefprozil Anhydrous, (E)- SCHEMBL14108301 | 1.00 | PTGS2 (1.00) | PTGS2DRD2DRD3MAPTALDH1A1 | |
| Cefprozil SCHEMBL37024 | 1.00 | PTGS2 (1.00) | PTGS2DRD2DRD3MAPTALDH1A1 | |
| Cefprozil Anhydrous, (E)- SCHEMBL5191958 | 1.00 | PTGS2 (1.00) | PTGS2DRD2DRD3MAPTALDH1A1 | |
| Cefprozil Anhydrous, (E)- SCHEMBL10801275 | 1.00 | PTGS2 (1.00) | PTGS2DRD2DRD3MAPTALDH1A1 | |
| Cefprozil Anhydrous, (E)- SCHEMBL7586258 | 1.00 | PTGS2 (1.00) | PTGS2DRD2DRD3MAPTALDH1A1 | |
| Cefprozil Anhydrous, (E)- SCHEMBL2901170 | 1.00 | PTGS2 (1.00) | PTGS2DRD2DRD3MAPTALDH1A1 | |
| Cefprozil Anhydrous, (E)- SCHEMBL14064854 | 1.00 | PTGS2 (1.00) | PTGS2DRD2DRD3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108403700-A | A kind of cattle respiratory disease treatment composite injection | 新疆生产建设兵团第师畜牧兽医工作站 | 2018-08-17 | — | — | CN | claimed |
| CN-102836129-B | Cefprozil dry suspension and preparation method thereof | NANJING YIHUA PHARMACEUTICAL CO LTD | 2014-06-11 | — | — | CN | claimed |
| CN-109971743-B | Penicillin G acylase mutant derived from achromobacter CCM4824 and application thereof | 艾美科健株式会社 | 2022-09-06 | — | — | CN | disclosed |
| CN-110960498-A | Preparation method of heat-unstable pharmaceutical composition | 南京亿华药业有限公司 | 2020-04-07 | — | — | CN | disclosed |
| CN-109971743-A | From the penicillin G acylase mutant of achromobacter CCM4824 and its application | 艾美科健株式会社 | 2019-07-05 | — | — | CN | disclosed |
| CN-109971742-A | From the penicillin G acylase mutant of achromobacter CCM 4824 and its application | 艾美科健株式会社 | 2019-07-05 | — | — | CN | disclosed |
| CN-108586492-A | A kind of preparation method of drug that treating infectious diseases | 湖南博隽生物医药有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-108403700-A | A kind of cattle respiratory disease treatment composite injection | 新疆生产建设兵团第师畜牧兽医工作站 | 2018-08-17 | — | — | CN | disclosed |
| CN-108017657-A | A kind of process for purification of Cefprozil | 山东裕欣药业有限公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-106177968-A | The preparation of the medicinal microsphere of a kind of silicon dioxide and in the application of pharmaceutical field | 河南中帅医药科技股份有限公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-103432076-B | Cefprozil dry suspension and preparation method thereof | Hainan gourd doll pharmaceutical co ltd | 2015-05-13 | — | — | CN | disclosed |
| CN-102846564-B | A cefprozil tablet and its preparation method | NANJING YIHUA PHARMACEUTICAL CO LTD | 2013-10-09 | — | — | CN | disclosed |
| CN-102846564-A | A cefprozil tablet and its preparation method | NANJING YIHUA PHARMACEUTICAL CO LTD | 2013-01-02 | — | — | CN | disclosed |
| CN-102836129-A | Cefprozil dry suspension and preparation method thereof | NANJING YIHUA PHARMACEUTICAL CO LTD | 2012-12-26 | — | — | CN | disclosed |
| CN-101953780-B | Cefprozil solid preparation and preparation method thereof | CSPC PHARMACEUTICAL GROUP OUYI PHARMA CO LTD | 2012-09-05 | — | — | CN | disclosed |
| CN-102038646-A | Sugar-free cefprozil dry suspension and preparation method thereof | SHANDONG LUKANG PHARMACEUTICAL CO LTD | 2011-05-04 | — | — | CN | disclosed |
| CN-101953780-A | Cefprozil solid preparation and preparation method thereof | SHIJIAZHUANG OUYI PHARMA CO LTD | 2011-01-26 | — | — | CN | disclosed |
| US-4661590-A | BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1987-04-28 | — | — | US | disclosed |
| US-4591641-A | ORAL ANTIBIOTICS; GRAM NEGATIVE AND GRAM POSITIVE BACTERIA ACTIVITY | BRISTOL-MYERS COMPANY (US) | 1986-05-27 | — | — | US | disclosed |
| US-4520022-A | BACTERIAL INFECTION IN MAMMALS | BRISTOL-MYERS COMPANY (US) | 1985-05-28 | — | — | US | disclosed |