Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | HPGD | P15428 | 7/20 | 0.46 |
| ▸ | CASP1 | P29466 | 6/20 | 0.46 |
| ▸ | CASP7 | P55210 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | GLA | P06280 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 7/20 | 0.45 |
| ▸ | CA9 | Q16790 | 7/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.45 |
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | CA7 | P43166 | 4/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10598804 | 0.83 | ADSS2 (0.38) | ALDH1A1KDM4EHPGDCASP1CASP7 | |
| SCHEMBL10801263 | 0.83 | ADSS2 (0.38) | ALDH1A1KDM4EHPGDCASP1CASP7 | |
| SCHEMBL10749528 | 0.81 | CA12 (0.53) | ALDH1A1KDM4EHPGDCASP1CASP7 | |
| SCHEMBL7198200 | 0.77 | CA12 (0.52) | ALDH1A1KDM4EHPGDCASP1CASP7 | |
| SCHEMBL188065 | 0.75 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDCASP1CASP7 | |
| SCHEMBL8021414 | 0.74 | TDP1 (0.48) | ALDH1A1KDM4EHPGDCASP1CASP7 | |
| SCHEMBL9118857 | 0.74 | TDP1 (0.48) | ALDH1A1KDM4EHPGDCASP1CASP7 | |
| SCHEMBL1581949 | 0.74 | TDP1 (0.48) | ALDH1A1KDM4EHPGDCASP1CASP7 | |
| SCHEMBL2343404 | 0.74 | TDP1 (0.48) | ALDH1A1KDM4EHPGDCASP1CASP7 | |
| SCHEMBL28237927 | 0.71 | SLC5A2 (0.38) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4687735-A | OXIDOREDUCTASES | SYNTEX (U.S.A.) INC. (US) | 1987-08-18 | — | — | US | disclosed |
| US-4629690-A | COMPETITIVE PROTEIN BINDING USING A SECOND ENZYME RELATED TO THE FIRST BY THE PRODUCT OF ONE BEING THE SUBSTRATE OF THE OTHER | SYNTEX (U.S.A.) INC. (US) | 1986-12-16 | — | — | US | disclosed |
| US-4233402-A | CHEMICAL ANALYSIS OF A BINDING PAIR OF LIGANDS AND ENZYMES BY LIGHT SIGNALS | SYVA COMPANY (US) | 1980-11-11 | — | — | US | disclosed |