Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | DHODH | Q02127 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10800942 | 0.93 | ALDH1A1 (0.52) | ALDH1A1TSHRDHODHL3MBTL1SMN1; SMN2 | |
| SCHEMBL2406505 | 0.83 | ALDH1A1 (0.76) | ALDH1A1TSHRDHODHL3MBTL1SMN1; SMN2 | |
| SCHEMBL1565743 | 0.83 | ALDH1A1 (0.76) | ALDH1A1TSHRDHODHL3MBTL1SMN1; SMN2 | |
| SCHEMBL22756633 | 0.82 | ALDH1A1 (0.72) | ALDH1A1TSHRDHODHL3MBTL1MEN1 | |
| SCHEMBL3330158 | 0.81 | MEN1 (0.71) | ALDH1A1TSHRDHODHL3MBTL1SMN1; SMN2 | |
| SCHEMBL14335367 | 0.81 | ALDH1A1 (0.80) | ALDH1A1TSHRDHODHL3MBTL1SMN1; SMN2 | |
| SCHEMBL4859453 | 0.81 | ALDH1A1 (0.71) | ALDH1A1TSHRDHODHL3MBTL1MEN1 | |
| SCHEMBL10806154 | 0.81 | ALDH1A1 (0.71) | ALDH1A1TSHRDHODHL3MBTL1MEN1 | |
| SCHEMBL20990440 | 0.80 | ALDH1A1 (0.74) | ALDH1A1TSHRDHODHL3MBTL1MEN1 | |
| SCHEMBL659023 | 0.80 | ALDH1A1 (0.74) | ALDH1A1TSHRDHODHL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159254-B1 | DERIVATIVES OF OMEGA-MERCAPTOPROPANAMIDE AND THEIR SALTS, THEIR PREPARATION, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1987-10-07 | — | — | EP | disclosed |
| EP-0159254-A1 | Derivatives of omega-mercaptopropanamide and their salts, their preparation, their use as medicines and compositions containing them | ROUSSEL-UCLAF (FR) | 1985-10-23 | — | — | EP | disclosed |