Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 2/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10803018 | 0.81 | SLC2A1 (0.52) | SLC2A1CYP2C19HTTPTK2NQO2 | |
| SCHEMBL10507503 | 0.80 | CYP2C19 (0.52) | SLC2A1CYP2C19HTTPTK2NQO2 | |
| SCHEMBL10506617 | 0.79 | SLC2A1 (0.48) | SLC2A1OPRK1CYP2C19HTTPTK2 | |
| SCHEMBL10507638 | 0.78 | SLC2A1 (0.47) | SLC2A1CYP2C19NQO2KDM4EALDH1A1 | |
| SCHEMBL10804993 | 0.77 | SLC2A1 (0.49) | SLC2A1CYP2C19HTTPTK2NQO2 | |
| SCHEMBL10801118 | 0.76 | SLC2A1 (0.48) | SLC2A1CYP2C19HTTNQO2ALDH1A1 | |
| SCHEMBL10506660 | 0.76 | TGFBR1 (0.40) | HTTPTK2 | |
| SCHEMBL18879034 | 0.76 | SLC2A1 (0.56) | SLC2A1HTTPTK2NQO2KDM4E | |
| SCHEMBL10506904 | 0.75 | NCF1 (0.56) | SLC2A1CYP2C19NQO2KDM4EALDH1A1 | |
| SCHEMBL10805500 | 0.74 | SLC2A1 (0.49) | SLC2A1CYP2C19HTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152910-B1 | PYRAZOLOPYRIDINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1989-07-12 | — | — | EP | disclosed |
| US-4670432-A | Pyrazolopyridine derivatives useful in treating inflammation and allergic conditions | BEECHAM GROUP P.L.C. (GB) | 1987-06-02 | — | — | US | disclosed |
| EP-0152910-A2 | pyrazolopyridine derivatives | BEECHAM GROUP PLC (GB) | 1985-08-28 | — | — | EP | disclosed |