Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10806658 | 0.85 | ALDH1A1 (0.52) | ALDH1A1ALDH3A1GAAMAPTLMNA | |
| SCHEMBL10802569 | 0.85 | ALDH1A1 (0.47) | ALDH1A1ALDH3A1GAAMAPTLMNA | |
| SCHEMBL10803999 | 0.84 | ALDH1A1 (0.49) | ALDH1A1ALDH3A1GAAMAPTLMNA | |
| SCHEMBL10803477 | 0.83 | ALDH1A1 (0.50) | ALDH1A1ALDH3A1GAAMAPTLMNA | |
| SCHEMBL10805882 | 0.83 | BCL9 (0.49) | ALDH1A1ALDH3A1GAAMAPTLMNA | |
| Butane SCHEMBL19371264 | 0.82 | ALDH1A1 (0.50) | ALDH1A1ALDH3A1GAAMAPTLMNA | |
| SCHEMBL13980532 | 0.82 | ALDH1A1 (0.59) | ALDH1A1GAAMAPTKMT2AMEN1 | |
| SCHEMBL11124304 | 0.81 | MAPT (0.48) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL10801357 | 0.81 | ALDH1A1 (0.45) | ALDH1A1ALDH3A1GAAMAPTLMNA | |
| SCHEMBL28280354 | 0.80 | ALDH1A1 (0.45) | ALDH1A1ALDH3A1GAAMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063101-B1 | NITROARYL-ALKYL-SULFONE DERIVATIVES AS GAMETOCIDES | CIBA-GEIGY AG (CH) | 1987-04-01 | — | — | EP | claimed |
| EP-0063101-A1 | Nitroaryl-alkyl-sulfone derivatives as gametocides | CIBA-GEIGY AG (CH) | 1982-10-20 | — | — | EP | claimed |
| EP-0063101-A1 | Nitroaryl-alkyl-sulfone derivatives as gametocides | CIBA-GEIGY AG (CH) | 1982-10-20 | — | — | EP | disclosed |