Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13048634 | 0.88 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL10806658 | 0.83 | ALDH1A1 (0.52) | ALDH1A1ALDH3A1MAPTMEN1RAB9A | |
| SCHEMBL13048608 | 0.82 | ALDH1A1 (0.52) | ALDH1A1MAPTRAB9AKDM4ELMNA | |
| SCHEMBL10805869 | 0.81 | ALDH1A1 (0.53) | ALDH1A1ALDH3A1MAPTMEN1RAB9A | |
| SCHEMBL4655499 | 0.80 | TTR (0.49) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL10803999 | 0.80 | ALDH1A1 (0.49) | ALDH1A1ALDH3A1MAPTMEN1RAB9A | |
| SCHEMBL10801379 | 0.79 | ALDH1A1 (0.39) | ALDH1A1MAPTMEN1RAB9AKMT2A | |
| SCHEMBL10805882 | 0.78 | BCL9 (0.49) | ALDH1A1ALDH3A1MAPTMEN1RAB9A | |
| SCHEMBL10803477 | 0.78 | ALDH1A1 (0.50) | ALDH1A1ALDH3A1MAPTMEN1RAB9A | |
| SCHEMBL9453022 | 0.78 | PTPN1 (0.51) | ALDH1A1ALDH3A1MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063101-B1 | NITROARYL-ALKYL-SULFONE DERIVATIVES AS GAMETOCIDES | CIBA-GEIGY AG (CH) | 1987-04-01 | — | — | EP | claimed |
| EP-0063101-A1 | Nitroaryl-alkyl-sulfone derivatives as gametocides | CIBA-GEIGY AG (CH) | 1982-10-20 | — | — | EP | claimed |
| EP-0063101-B1 | NITROARYL-ALKYL-SULFONE DERIVATIVES AS GAMETOCIDES | CIBA-GEIGY AG (CH) | 1987-04-01 | — | — | EP | disclosed |
| EP-0063101-A1 | Nitroaryl-alkyl-sulfone derivatives as gametocides | CIBA-GEIGY AG (CH) | 1982-10-20 | — | — | EP | disclosed |