Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 3/20 | 0.41 |
| ▸ | CDK4 | P11802 | 3/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.41 |
| ▸ | CCND1 | P24385 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9069463 | 0.82 | KDM4E (0.47) | SLC2A1LRRK2KDM4EALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL9073160 | 0.81 | KDM4E (0.46) | SLC2A1LRRK2KDM4EALDH1A1MEN1 | |
| SCHEMBL9070477 | 0.81 | KDM4E (0.45) | SLC2A1LRRK2KDM4EALDH1A1MEN1 | |
| SCHEMBL3003705 | 0.77 | KDM4E (0.46) | LRRK2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL18879034 | 0.76 | SLC2A1 (0.56) | SLC2A1KDM4EMAPTHTT | |
| SCHEMBL9069462 | 0.75 | KDM4E (0.40) | SLC2A1LRRK2KDM4EALDH1A1MEN1 | |
| SCHEMBL10803018 | 0.72 | SLC2A1 (0.52) | SLC2A1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL10817816 | 0.72 | SLC2A1 (0.59) | SLC2A1MAPTHTT | |
| Hydrochloric Acid SCHEMBL11846718 | 0.69 | IP6K1 (0.44) | LRRK2ALDH1A1HSD17B10ADORA2AADORA1 | |
| SCHEMBL10805234 | 0.69 | SLC2A1 (0.74) | SLC2A1KDM4EMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119774-B1 | ANTI-INFLAMMATORY PYRAZOLO PYRIDINES | BEECHAM GROUP PLC (GB) | 1987-06-24 | — | — | EP | claimed |
| US-4559348-A | SKIN DISORDERS | BEECHAM GROUP, P.L.C. (GB) | 1985-12-17 | — | — | US | claimed |
| EP-0119774-A1 | Anti-inflammatory pyrazolo pyridines | BEECHAM GROUP PLC (GB) | 1984-09-26 | — | — | EP | claimed |
| EP-0119774-B1 | ANTI-INFLAMMATORY PYRAZOLO PYRIDINES | BEECHAM GROUP PLC (GB) | 1987-06-24 | — | — | EP | disclosed |
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| US-4559348-A | SKIN DISORDERS | BEECHAM GROUP, P.L.C. (GB) | 1985-12-17 | — | — | US | disclosed |
| EP-0119774-A1 | Anti-inflammatory pyrazolo pyridines | BEECHAM GROUP PLC (GB) | 1984-09-26 | — | — | EP | disclosed |