Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CDK4 | P11802 | 2/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.38 |
| ▸ | CCND1 | P24385 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9069463 | 0.99 | KDM4E (0.47) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9073160 | 0.98 | KDM4E (0.46) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9069462 | 0.93 | KDM4E (0.40) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9376581 | 0.84 | KDM4E (0.44) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10805916 | 0.81 | SLC2A1 (0.47) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9370791 | 0.79 | MEN1 (0.46) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11846718 | 0.77 | IP6K1 (0.44) | ALDH1A1HSD17B10LRRK2ADORA2AADORA1 | |
| SCHEMBL9073073 | 0.76 | PTGS1 (0.43) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9069382 | 0.75 | PTGS1 (0.43) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9073452 | 0.75 | L3MBTL1 (0.53) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506235-A | Quinoline derivatives as immunostimulants | PFIZER INC. (US) | 1996-04-09 | — | — | US | disclosed |