Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | CETP | P11597 | 4/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | PTAFR | P25105 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | P2RY10 | O00398 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.40 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.40 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10804674 | 0.96 | PPARA (0.47) | PPARAPPARGCETPADRA1DPTAFR | |
| SCHEMBL10805739 | 0.91 | PPARA (0.47) | PPARAPPARGCETPGGPS1 | |
| SCHEMBL10813542 | 0.89 | S1PR1 (0.51) | CETPADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL10806442 | 0.89 | S1PR1 (0.51) | CETPADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL10817789 | 0.88 | PPARA (0.49) | PPARAPPARGCETPP2RY10S1PR4 | |
| SCHEMBL9651352 | 0.87 | PPARA (0.54) | PPARAPPARGP2RY10S1PR4S1PR1 | |
| SCHEMBL10808732 | 0.85 | S1PR1 (0.51) | CETPADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL10807984 | 0.85 | S1PR1 (0.51) | CETPADRA1DPTAFRHTR1DHTR2C | |
| SCHEMBL10809708 | 0.82 | ADRA1D (0.45) | PPARAPPARGCETPADRA1DPTAFR | |
| SCHEMBL10806823 | 0.80 | PPARA (0.47) | PPARAPPARGADRA1DPTAFRHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4640913-A | Phosphocholine derivatives having antihypertensive action | AMERICAN CYANAMID COMPANY (US) | 1987-02-03 | — | — | US | disclosed |