Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.66 |
| ▸ | ACE | P12821 | 3/20 | 0.58 |
| ▸ | CTSS | P25774 | 3/20 | 0.55 |
| ▸ | CTSK | P43235 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.49 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10805078 | 0.88 | CTSL (0.64) | CTSLACECTSSCTSKGAA | |
| SCHEMBL10802761 | 0.87 | CTSL (0.52) | CTSLACECTSSCTSKGAA | |
| SCHEMBL10799841 | 0.84 | CTSL (0.63) | CTSLACECTSSCTSKGAA | |
| SCHEMBL10817131 | 0.83 | ACE (0.50) | CTSLACECTSSCTSKGAA | |
| SCHEMBL10801723 | 0.83 | CTSL (0.48) | CTSLACECTSSCTSKGAA | |
| SCHEMBL10817136 | 0.82 | CTSL (0.47) | CTSLACECTSSCTSKGAA | |
| SCHEMBL19437162 | 0.82 | CTSL (0.71) | CTSLACECTSSCTSKGAA | |
| SCHEMBL20838261 | 0.82 | CTSL (0.71) | CTSLACECTSSCTSKGAA | |
| SCHEMBL3927028 | 0.82 | CTSL (0.71) | CTSLACECTSSCTSKGAA | |
| SCHEMBL28790851 | 0.82 | CTSL (0.71) | CTSLACECTSSCTSKGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0134561-B1 | ALPHA-ALLENIC-ALPHA-AMINO ACIDS | SYNTEX (U.S.A.) INC. (US) | 1987-07-08 | — | — | EP | disclosed |
| US-4661510-A | FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1987-04-28 | — | — | US | disclosed |
| EP-0134561-A1 | Alpha-allenic-alpha-amino acids | SYNTEX (U.S.A.) INC. (US) | 1985-03-20 | — | — | EP | disclosed |