Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10805989 | 0.83 | CTSL (0.66) | CTSLALDH1A1CTSSCTSKCTSB | |
| SCHEMBL31248369 | 0.82 | ALDH1A1 (0.54) | CTSLALDH1A1NPC1ADRB2ADRB1 | |
| SCHEMBL10802099 | 0.82 | ALDH1A1 (0.57) | CTSLALDH1A1NPC1ADRB2ADRB1 | |
| SCHEMBL10815966 | 0.81 | ALDH1A1 (0.46) | CTSLALDH1A1HPGDRECQLNPC1 | |
| SCHEMBL10805078 | 0.80 | CTSL (0.64) | CTSLALDH1A1CTSSCTSKACE | |
| SCHEMBL10805329 | 0.80 | CTSL (0.43) | CTSLALDH1A1HPGDRECQLNPC1 | |
| SCHEMBL10799987 | 0.79 | FOLH1 (0.46) | CTSLHPGDRECQLNPC1CA1 | |
| SCHEMBL576636 | 0.78 | NPC1 (0.69) | ALDH1A1HPGDRECQLNPC1CA12 | |
| SCHEMBL10805205 | 0.78 | FOLH1 (0.50) | NPC1CA1CA2RAB9A | |
| SCHEMBL10805325 | 0.77 | RECQL (0.43) | CTSLALDH1A1HPGDRECQLNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4661510-A | FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1987-04-28 | — | — | US | disclosed |