Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.45 |
| ▸ | CTSS | P25774 | 5/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10805594 | 0.79 | CTSK (0.47) | CTSKCTSS | |
| SCHEMBL15110725 | 0.76 | CA1 (0.49) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL10806402 | 0.75 | CTSK (0.46) | CTSKCA1CA2CA7 | |
| SCHEMBL4801958 | 0.75 | CTSK (0.46) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL7349501 | 0.75 | CTSK (0.47) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL1319454 | 0.74 | NAALAD2 (0.59) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL20745305 | 0.74 | NAALAD2 (0.59) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL7066210 | 0.74 | NAALAD2 (0.59) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL13263380 | 0.74 | NAALAD2 (0.59) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL18560556 | 0.74 | NAALAD2 (0.59) | CTSKCTSSCTSLCTSBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0134481-B1 | GAMMA-ALLENYL-GAMMA-AMINOBUTYRIC ACIDS | SYNTEX (U.S.A.) INC. (US) | 1987-12-16 | — | — | EP | claimed |