Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.59 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.59 |
| ▸ | CTSK | P43235 | 6/20 | 0.52 |
| ▸ | CTSS | P25774 | 5/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1319454 | 1.00 | NAALAD2 (0.59) | NAALAD2FOLH1CTSKCTSSCTSL | |
| SCHEMBL7954021 | 1.00 | NAALAD2 (0.59) | NAALAD2FOLH1CTSKCTSSCTSL | |
| SCHEMBL7066210 | 1.00 | NAALAD2 (0.59) | NAALAD2FOLH1CTSKCTSSCTSL | |
| SCHEMBL20745305 | 1.00 | NAALAD2 (0.59) | NAALAD2FOLH1CTSKCTSSCTSL | |
| SCHEMBL13263380 | 1.00 | NAALAD2 (0.59) | NAALAD2FOLH1CTSKCTSSCTSL | |
| SCHEMBL28804956 | 0.90 | CTSK (0.50) | NAALAD2FOLH1CTSKCTSSCTSL | |
| SCHEMBL28804957 | 0.90 | CTSK (0.50) | NAALAD2FOLH1CTSKCTSSCTSL | |
| SCHEMBL27844888 | 0.89 | CTSK (0.57) | NAALAD2FOLH1CTSKCTSSCTSL | |
| SCHEMBL30174879 | 0.89 | CTSK (0.49) | NAALAD2FOLH1CTSKCTSSCTSL | |
| SCHEMBL13293190 | 0.89 | CTSK (0.49) | NAALAD2FOLH1CTSKCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2953932-B1 | SUBSTITUTED CARBOXYLIC ACID DERIVATIVES AS AGGRECANASE INHIBITORS FOR THE TREATMENT OF OSTEOARTHRITIS | MERCK PATENT GMBH (DE) | 2017-03-01 | — | — | EP | disclosed |
| CN-102206247-B | Novel peptides as NS3/NS4a serine protease inhibitors of hepatitis C virus | DENDREON CORP | 2013-03-27 | — | — | CN | disclosed |