Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.72 |
| ▸ | MEN1 | O00255 | 9/20 | 0.72 |
| ▸ | MAPT | P10636 | 7/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | HTT | P42858 | 4/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.69 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.69 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.69 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.69 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.69 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10922701 | 0.92 | KMT2A (0.72) | BAZ1AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL10962764 | 0.91 | KMT2A (0.74) | BAZ1AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL24340403 | 0.90 | KMT2A (0.69) | BAZ1AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL15689083 | 0.90 | RAB9A (0.73) | BAZ1AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL10919656 | 0.88 | KMT2A (0.67) | BAZ1AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL21586297 | 0.87 | KMT2A (0.75) | BAZ1AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL15688998 | 0.87 | MEN1 (0.87) | BAZ1AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8684018 | 0.86 | CSNK2A1 (0.67) | BAZ1AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL3593035 | 0.86 | CSNK2A1 (0.67) | BAZ1AKMT2AMEN1MAPTALDH1A1 | |
| Bromide SCHEMBL7146574 | 0.85 | KMT2A (0.68) | BAZ1AKMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0069784-B1 | THIAZOLYLUREA DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND MEDICINAL COMPOSITION CONTAINING SAME | MITSUI TOATSU KAGAKU KABUSHIKI KAISHA (JP) | 1987-12-16 | — | — | EP | disclosed |
| US-4490393-A | Thiazolylurea derivatives, a process for preparing same and a pharmaceutical composition containing same | Mitsui Toatsu Kagaki Kabushiki Kaisha (JP) | 1984-12-25 | — | — | US | disclosed |
| EP-0069784-A1 | THIAZOLYLUREA DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND MEDICINAL COMPOSITION CONTAINING SAME | MITSUI TOATSU KAGAKU KABUSHIKI KAISHA (JP) | 1983-01-19 | — | — | EP | disclosed |