Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.69 |
| ▸ | MEN1 | O00255 | 9/20 | 0.69 |
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.69 |
| ▸ | VCP | P55072 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.67 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.67 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.67 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.67 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10919656 | 0.91 | KMT2A (0.67) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL10922701 | 0.90 | KMT2A (0.72) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL10808167 | 0.90 | BAZ1A (0.79) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL3593035 | 0.89 | CSNK2A1 (0.67) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL8684018 | 0.89 | CSNK2A1 (0.67) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL10962764 | 0.89 | KMT2A (0.74) | KMT2AMEN1MAPTALDH1A1HTT | |
| Bromide SCHEMBL7146574 | 0.88 | KMT2A (0.68) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL15689083 | 0.88 | RAB9A (0.73) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL21586297 | 0.85 | KMT2A (0.75) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL15688998 | 0.85 | MEN1 (0.87) | KMT2AMEN1MAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3325452-B1 | SUBSTITUTED HYDROPHOBIC BENZENE SULFONAMIDE THIAZOLE COMPOUNDS FOR USE IN TREATING CANCER | INST NAT SANTE RECH MED (FR) | 2022-03-30 | — | — | EP | disclosed |