Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.47 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10811375 | 1.00 | PADI1 (0.47) | PADI1PADI4TSHRMEN1KMT2A | |
| SCHEMBL10809124 | 0.88 | PADI1 (0.47) | PADI1PADI4TSHRMEN1KMT2A | |
| SCHEMBL10813060 | 0.85 | PADI1 (0.45) | PADI1PADI4TSHRMEN1KMT2A | |
| SCHEMBL5209318 | 0.84 | SMN1; SMN2 (0.47) | PADI1PADI4TSHRMEN1KMT2A | |
| SCHEMBL10808068 | 0.82 | PADI1 (0.43) | PADI1PADI4TSHRMEN1KMT2A | |
| SCHEMBL10808220 | 0.79 | HPGD (0.42) | TSHRKMT2AEPHX1ALDH1A1 | |
| SCHEMBL10809089 | 0.79 | TDP1 (0.40) | PADI1PADI4TSHRMEN1KMT2A | |
| SCHEMBL5113817 | 0.78 | MEN1 (0.48) | MEN1KMT2ALMNAEPHX1ALDH1A1 | |
| SCHEMBL15636544 | 0.78 | MEN1 (0.41) | PADI1PADI4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13397295 | 0.76 | PADI1 (0.39) | PADI1PADI4MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0096890-B1 | OXAZOLEACETIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND COMPOSITIONS CONTAINING SAID DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 1987-11-25 | — | — | EP | disclosed |
| US-4602027-A | HYPOGLYCEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-07-22 | — | — | US | disclosed |
| EP-0096890-A2 | Oxazoleacetic acid derivatives, process for their production and compositions containing said derivatives | Takeda Chemical Industries, Ltd. (JP) | 1983-12-28 | — | — | EP | disclosed |