Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.46 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | F2R | P25116 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898517 | 0.86 | MME (0.46) | SMN1; SMN2PADI1PADI4CASP3LMNA | |
| SCHEMBL23967395 | 0.86 | MME (0.46) | SMN1; SMN2PADI1PADI4CASP3LMNA | |
| SCHEMBL28910144 | 0.85 | MME (0.45) | SMN1; SMN2PADI1PADI4CASP3LMNA | |
| SCHEMBL10808294 | 0.84 | PADI1 (0.47) | SMN1; SMN2PADI1PADI4TSHRLMNA | |
| SCHEMBL10811375 | 0.84 | PADI1 (0.47) | SMN1; SMN2PADI1PADI4TSHRLMNA | |
| SCHEMBL24786205 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2PADI1PADI4CASP3LMNA | |
| SCHEMBL25206154 | 0.77 | LMNA (0.47) | CASP3LMNAGAA | |
| SCHEMBL25206156 | 0.77 | LMNA (0.47) | CASP3LMNAGAA | |
| SCHEMBL6502285 | 0.76 | PADI1 (0.45) | SMN1; SMN2PADI1PADI4LMNAHDAC8 | |
| SCHEMBL5113817 | 0.75 | MEN1 (0.48) | CASP3LMNAMEN1KMT2APSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313716-B1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | LILLY CO ELI (US) | 2007-05-02 | — | — | EP | disclosed |