Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 9/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CASP2 | P42575 | 1/20 | 0.55 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.52 |
| ▸ | CPT2 | P23786 | 1/20 | 0.51 |
| ▸ | CPT1A | P50416 | 1/20 | 0.51 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342142 | 1.00 | EPHX1 (0.76) | EPHX1SMN1; SMN2CASP2ASAH2CPT2 | |
| SCHEMBL12196042 | 0.86 | EPHX1 (1.00) | EPHX1SMN1; SMN2 | |
| SCHEMBL25834895 | 0.86 | EPHX1 (1.00) | EPHX1SMN1; SMN2 | |
| SCHEMBL13777205 | 0.86 | EPHX1 (1.00) | EPHX1SMN1; SMN2 | |
| SCHEMBL27052608 | 0.86 | EPHX1 (1.00) | EPHX1SMN1; SMN2 | |
| SCHEMBL9784658 | 0.86 | EPHX1 (1.00) | EPHX1SMN1; SMN2 | |
| SCHEMBL1896879 | 0.84 | EPHX1 (0.96) | EPHX1SMN1; SMN2CPT2CPT1ACPT1B | |
| SCHEMBL25853703 | 0.83 | EPHX1 (0.73) | EPHX1SMN1; SMN2CPT2CPT1ACPT1B | |
| SCHEMBL11780964 | 0.83 | EPHX1 (0.73) | EPHX1SMN1; SMN2CPT2CPT1ACPT1B | |
| SCHEMBL4587111 | 0.81 | EPHX1 (0.71) | EPHX1SMN1; SMN2CPT2CPT1ACPT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4710580-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-12-01 | — | — | US | disclosed |