SCHEMBL25853703

SCHEMBL25853703

CCCCCCCCCCCCCCCCNC(=O)NC(C)CC

nearest known ligand 0.73

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 9/20 0.73
SMN1; SMN2 Q16637 1/20 0.60
EPHX2 P34913 2/20 0.56
CPT2 P23786 1/20 0.50
CPT1A P50416 1/20 0.50
CPT1B Q92523 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23479917 0.91 EPHX1 (0.61) EPHX1EPHX2
SCHEMBL19370276 0.87 EPHX1 (0.71) EPHX1SMN1; SMN2CPT2CPT1ACPT1B
SCHEMBL19370275 0.87 EPHX1 (0.71) EPHX1SMN1; SMN2CPT2CPT1ACPT1B
SCHEMBL12217817 0.86 EPHX1 (0.69) EPHX1SMN1; SMN2EPHX2CPT2CPT1A
SCHEMBL27052608 0.85 EPHX1 (1.00) EPHX1SMN1; SMN2EPHX2
SCHEMBL12196042 0.85 EPHX1 (1.00) EPHX1SMN1; SMN2EPHX2
SCHEMBL9784658 0.85 EPHX1 (1.00) EPHX1SMN1; SMN2EPHX2
SCHEMBL25834895 0.85 EPHX1 (1.00) EPHX1SMN1; SMN2EPHX2
SCHEMBL13777205 0.85 EPHX1 (1.00) EPHX1SMN1; SMN2EPHX2
SCHEMBL10808317 0.83 EPHX1 (0.76) EPHX1SMN1; SMN2CPT2CPT1ACPT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 EPHX1 3890/4885SMN1; SMN2 155/4885EPHX2 3168/4885
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 EPHX1 4523/4885SMN1; SMN2 52/4885EPHX2 4580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.