Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10554129 | 0.80 | CYP2D6 (0.44) | LMNAKDM4EALDH1A1CERT1ASAH1 | |
| SCHEMBL10550537 | 0.80 | LMNA (0.53) | LMNAKDM4EALDH1A1CERT1ASAH1 | |
| SCHEMBL8506852 | 0.70 | LMNA (0.51) | LMNAHPGDHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL10720279 | 0.70 | POLB (0.39) | LMNAHPGDHIF1AHSD17B10KDM4E | |
| SCHEMBL10702860 | 0.69 | LMNA (0.48) | LMNAHPGDHIF1AHSD17B10ALDH1A1 | |
| 1,4-Butanediol SCHEMBL8980142 | 0.69 | LMNA (0.49) | LMNAHPGDHIF1AHSD17B10ALDH1A1 | |
| 1,3-Propanediol SCHEMBL8503984 | 0.69 | LMNA (0.49) | LMNAHPGDHIF1AHSD17B10ALDH1A1 | |
| Ethylene Glycol SCHEMBL6331832 | 0.69 | LMNA (0.51) | LMNAHPGDHIF1AHSD17B10ALDH1A1 | |
| Benzoin SCHEMBL8764252 | 0.69 | LMNA (0.54) | LMNAHPGDHIF1AHSD17B10KDM4E | |
| Alcohol SCHEMBL19458443 | 0.69 | LMNA (0.57) | LMNAKDM4EALDH1A1CERT1ASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117476-B1 | TETRAHYDROPYRANES | MERCK PATENT GmbH (DE) | 1987-09-16 | — | — | EP | disclosed |
| EP-0117476-A1 | Tetrahydropyranes | MERCK PATENT GmbH (DE) | 1984-09-05 | — | — | EP | disclosed |