Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121153 | 0.88 | LMNA (0.53) | LMNAHPGDHIF1AHSD17B10RECQL | |
| Ammonia Solution, Strong SCHEMBL1924833 | 0.86 | LMNA (0.51) | LMNAHPGDHIF1AHSD17B10RECQL | |
| Hydrochloric Acid SCHEMBL5858440 | 0.86 | LMNA (0.51) | LMNAHPGDHIF1AHSD17B10RECQL | |
| Water SCHEMBL3002925 | 0.86 | LMNA (0.51) | LMNAHPGDHIF1AHSD17B10RECQL | |
| Ethylene Glycol SCHEMBL6331832 | 0.84 | LMNA (0.51) | LMNAHPGDHIF1AHSD17B10RECQL | |
| SCHEMBL3369695 | 0.83 | LMNA (0.51) | LMNAHPGDHIF1AHSD17B10RECQL | |
| Isopropylamine SCHEMBL2350745 | 0.83 | LMNA (0.46) | LMNAHPGDHIF1AHSD17B10RECQL | |
| Ethylenediamine SCHEMBL8311256 | 0.83 | LMNA (0.50) | LMNAHPGDHIF1AHSD17B10RECQL | |
| SCHEMBL2919989 | 0.82 | LMNA (0.50) | LMNAHPGDHIF1AHSD17B10RECQL | |
| 1,4-Butanediol SCHEMBL8980142 | 0.81 | LMNA (0.49) | LMNAHPGDHIF1AHSD17B10RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0940403-A2 | Process for the preparation of macropolycyclic polyamines | Clariant GmbH (DE) | 1999-09-08 | — | — | EP | disclosed |