SCHEMBL10808441

SCHEMBL10808441

CC(C)(c1cc(Br)cc(Br)c1OCCCCBr)c1cc(Br)cc(Br)c1OCCCCBr

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KLK1 P06870 1/20 0.38
ALDH1A1 P00352 4/20 0.36
KDM4E B2RXH2 4/20 0.35
THRA P10827 4/20 0.34
THRB P10828 4/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
HRH3 Q9Y5N1 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19182349 0.95 ALDH1A1 (0.36) KLK1ALDH1A1KDM4ETHRATHRB
SCHEMBL7141326 0.85 PTGDR2 (0.35) KLK1ALDH1A1KDM4ETHRATHRB
SCHEMBL4611743 0.80 PTGDR2 (0.36) KLK1ALDH1A1KDM4ETHRATHRB
SCHEMBL12370664 0.77 KLK1 (0.44) KLK1ALDH1A1KDM4ETHRATHRB
SCHEMBL9807440 0.75 ALDH1A1 (0.66) ALDH1A1
SCHEMBL9240974 0.74 KLK1 (0.53) KLK1ALDH1A1KDM4ETHRATHRB
SCHEMBL12370674 0.73 ALDH1A1 (0.58) KLK1ALDH1A1KDM4ETHRATHRB
SCHEMBL11451332 0.72 KLK1 (0.57) KLK1ALDH1A1KDM4ETHRATHRB
SCHEMBL11450662 0.72 KLK1 (0.57) KLK1ALDH1A1KDM4ETHRATHRB
SCHEMBL30340743 0.72 THRB (0.38) KDM4ETHRATHRBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4649219-A CROSSLINKERS, ADHESIVES, PAINTS MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1987-03-10 US disclosed